anti-小鼠 FZD7 抗体 for Immunohistochemistry

Recommended FZD7 Antibody (supplied by: Log in to see )

抗原
Frizzled Family Receptor 7 (FZD7) 抗体
  • Fz-7
  • Xfz7
  • frizzled-7
  • frizzled7
  • frz-7
  • frz7
  • fz7
  • fze3
  • FzE3
  • fzd7-a
  • fzd7-b
  • cFz-7
  • Fz7
  • frizzled class receptor 7
  • frizzled class receptor 7 L homeolog
  • cyclin-dependent kinase 15
  • FZD7
  • fzd7
  • fzd7.L
  • Cdk15
  • Fzd7
抗原表位
C-Term
27
18
18
16
15
10
9
8
7
3
3
2
2
2
2
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 人, 小鼠, 猪, 兔, 大鼠, Yeast (Saccharomyces cerevisiae)
143
117
29
9
9
9
7
7
6
3
2
1
1
宿主

112
39
25
10
1
克隆类型
多克隆
标记
This FZD7 antibody is un-conjugated
11
6
5
5
5
4
4
4
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
123
74
28
23
22
14
13
5
2
2
2
1
1
选项
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产品编号 ABIN2776708
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.538242 ABIN337331 ELISA IHC IHC (p) WB Goat AA 559-572 Log in to see Polyclonal 0
8.538242 ABIN1048627 IHC IHC (p) Rabbit N-Term Log in to see Polyclonal 0
8.538242 ABIN213489 ELISA IHC IHC (p) Rabbit C-Term Log in to see Polyclonal 0
8.538242 ABIN2469409 IHC ELISA Rabbit C-Term Log in to see Polyclonal 0
8.538242 ABIN635842 IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN216661 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN4312613 IHC IHC (p) Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2462375 IHC ELISA WB Rabbit Log in to see Polyclonal 0
1 ABIN393087 FACS IHC ELISA Biotin Rat IgG2a Cysteine-Rich Domain, Extracellular Log in to see 0
1 ABIN478760 IHC ELISA WB Goat IgG AA 33-185 Log in to see Polyclonal 0
1 ABIN2269698 IC FACS IHC ELISA Biotin Rat IgG2a AA 33-185 Log in to see 9j129 0
1 ABIN2269696 IHC ELISA WB Goat IgG Log in to see Polyclonal 0

General

抗原 Frizzled Family Receptor 7 (FZD7) 抗体
抗原表位 C-Term
(27), (18), (18), (16), (15), (10), (9), (8), (7), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 人, 小鼠, 猪, 兔, 大鼠, Yeast (Saccharomyces cerevisiae)
(143), (117), (29), (9), (9), (9), (7), (7), (6), (3), (2), (1), (1)
宿主
(112), (39), (25), (10), (1)
克隆类型
多克隆
标记 This FZD7 antibody is un-conjugated
(11), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(123), (74), (28), (23), (22), (14), (13), (5), (2), (2), (2), (1), (1)
Pubmed 6个引用可参考
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FZD7抗体详情

FZD7目标详情 使用细节 贮存及处理 References for anti-FZD7 antibody (ABIN2776708) 图像
Blocking Peptide Blocking peptide for this product available: ABIN977173
序列 PDFTVFMIKY LMTMIVGITT GFWIWSGKTL QSWRRFYHRL SHSSKGETAV
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%
产品特性 This is a rabbit polyclonal antibody against FZD7. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human FZD7
Plasmids, Primers & others

FZD7目标详情

FZD7抗体详情 使用细节 贮存及处理 References for anti-FZD7 antibody (ABIN2776708) 图像 回页首
抗原
别名 FZD7 (FZD7 Antibody 摘要)
背景 FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Alias Symbols: FzE3
Protein Interaction Partner: UBC, UBQLN4, MAGI3, UBQLN1, DLG2, DLG4, DLG1,
Protein Size: 574
分子量 63 kDa
基因ID 8324
NCBI登录号 NM_003507, NP_003498
UniProt O75084
途径 WNT signaling, Stem Cell Maintenance

使用细节

FZD7抗体详情 FZD7目标详情 贮存及处理 References for anti-FZD7 antibody (ABIN2776708) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 574 AA

限制 仅限研究用

贮存及处理

FZD7抗体详情 FZD7目标详情 使用细节 References for anti-FZD7 antibody (ABIN2776708) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FZD7 antibody (ABIN2776708)

FZD7抗体详情 FZD7目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, 2012

Schmuck, Warneke, Behrens, Simon, Weichert, Röcken: "Genotypic and phenotypic characterization of side population of gastric cancer cell lines." in: The American journal of pathology, Vol. 178, Issue 4, pp. 1792-804, 2011

Gökmen-Polar, Toroni, Hocevar, Badve, Zhao, Shen, Bruckheimer, Kinch, Miller: "Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer." in: Breast cancer research and treatment, Vol. 127, Issue 2, pp. 375-84, 2011

Ohba, Lanigan, Roessler: "Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 18, Issue 12, pp. 1620-9, 2010

Ueno, Hiura, Suehiro, Hazama, Hirata, Oka, Imai, Dahiya, Hinoda: "Frizzled-7 as a potential therapeutic target in colorectal cancer." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 7, pp. 697-705, 2008

背景

Vincan, Darcy, Smyth, Thompson, Thomas, Phillips, Ramsay: "Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth." in: Differentiation; research in biological diversity, Vol. 73, Issue 4, pp. 142-53, 2005

图像

FZD7抗体详情 FZD7目标详情 使用细节 贮存及处理 References for anti-FZD7 antibody (ABIN2776708) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) WB Suggested Anti-FZD7 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...
Immunohistochemistry (IHC) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) Rabbit Anti-FZD7 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epit...
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) WB Suggested Anti-FZD7
Antibody Titration: 0.2-1 µg/mL
Positive Control...
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) Host: Rabbit Target Name: FZD7 Sample Tissue: Human A549 Whole Cell Antibody Di...
Western Blotting (WB) image for anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody (ABIN2776708) Host: Rabbit Target Name: FZD7 Sample Tissue: Human Ovary Tumor Antibody Diluti...