|抗原||Frizzled Family Receptor 6 (FZD6) 抗体|
|标记||This FZD6 antibody is un-conjugated 其他选择|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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|特异性||Reacts with Frizzled-6 (Family: GPCR, Subfamily: Frizzled)|
|纯化方法||Peptide Immunogen Affinity Chromatography.|
|免疫原||Synthetic peptide - KLH conjugated|
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|别名||FZD6 (FZD6 Antibody 摘要)|
|背景||FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled. FZD6 expression has been reported in brain, colon, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, testis, and thymus. Various tumor cell lines have also been shown to express FZD6. ESTs have been isolated from blood, brain, breast, connective tissue, liver, liver/spleen, lung, placenta, testis, thyroid, and vessel libraries. In addition, several ESTs have been isolated from tumor libraries.Synonyms: Frizzled-6, Fz-6, hFz6|
|途径||WNT signaling, Tube Formation|
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Immunocytochemistry. Immunohistochemistry with acetone fixed frozen and formalin fixed paraffin embedded tissues: 6-14 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
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|缓冲液||PBS containing 0.09 % Sodium Azide as preservative.|
|注意事项||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|储存条件||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
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