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|抗原||Casein Kinase 1, alpha 1 (CSNK1A1) 抗体|
|适用||人, 小鼠, 大鼠 其他选择|
|标记||This CSNK1A1 antibody is un-conjugated 其他选择|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
CSNK1A1抗体详情CSNK1A1目标详情 使用细节 贮存及处理 图像
|特异性||This antibody detects endogenous levels of Casein Kinase I α protein.|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|纯化方法||Affinity chromatography using epitope-specific immunogen|
|纯度||> 95 % (by SDS-PAGE)|
CSNK1A1目标详情CSNK1A1抗体详情 使用细节 贮存及处理 图像 回页首
|别名||Casein Kinase I alpha (CSNK1A1 Antibody 摘要)|
|背景||Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK1, CKI-alpha, CSNK1A1|
|分子量||approx. 35 kDa|
|途径||WNT signaling, Hedgehog Signaling|
使用细节CSNK1A1抗体详情 CSNK1A1目标详情 贮存及处理 图像 回页首
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
贮存及处理CSNK1A1抗体详情 CSNK1A1目标详情 使用细节 图像 回页首
|缓冲液||Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2|
|注意事项||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|注意事项||Avoid repeated freezing and thawing.|
|储存条件||4 °C/-20 °C|
|储存方法||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.|
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