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WEE1 Homolog (S. Pombe) 产品

(WEE1 Homolog (S. Pombe) (WEE1))

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This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008].

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Featured WEE1 Homolog (S. Pombe) Categories

WEE1 Homolog (S. Pombe) 抗体

High quality antibodies with extensive validation data.

WEE1 Homolog (S. Pombe) ELISA试剂盒

Reliable ELISA kits for a wide range of species.

WEE1 Homolog (S. Pombe) 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WEE1 Homolog (S. Pombe) 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN746873
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN756592
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN521378
Quantity 200 μL
Datasheet Datasheet

Recommended WEE1 Homolog (S. Pombe) ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380495
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended WEE1 Homolog (S. Pombe) 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5569878
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569925
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325304
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our WEE1 Homolog (S. Pombe) Products

Yue, Zhen, Huang, Zheng, Feng, Jiang, Yang, Wu, Liu, Guo: "Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159034, (2016) (PubMed).

Herzog, Fink, Weitmann, Friedel, Hadlich, Langner, Kindermann, Holm, Böhm, Eskilsson, Miletic, Hildner, Fritsch, Vogelgesang, Havemann, Ritter, Meyer zu Schwabedissen, Rauch, Hoffmann, Kroemer et al.: "Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. ..." in: Neuro-oncology, Vol. 17, Issue 2, pp. 223-42, (2015) (PubMed).

Ovejero, Ayala, Bueno, Sacristán: "Human Cdc14A regulates Wee1 stability by counteracting CDK-mediated phosphorylation." in: Molecular biology of the cell, Vol. 23, Issue 23, pp. 4515-25, (2012) (PubMed).

Müller, Lutter, Püschel: "Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity." in: Journal of cell science, Vol. 123, Issue Pt 2, pp. 286-94, (2010) (PubMed).

Li, Andrake, Dunbrack, Enders: "A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export." in: Molecular and cellular biology, Vol. 30, Issue 1, pp. 116-30, (2009) (PubMed).

Caffarel, Sarrió, Palacios, Guzmán, Sánchez: "Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation." in: Cancer research, Vol. 66, Issue 13, pp. 6615-21, (2006) (PubMed).

Yoshida, Tanaka, Mogi, Shitara, Kuwano: "The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer." in: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Vol. 15, Issue 2, pp. 252-6, (2004) (PubMed).

Watanabe, Arai, Nishihara, Taniguchi, Watanabe, Hunter, Osada: "M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 13, pp. 4419-24, (2004) (PubMed).

Dai, Yamasaki, Yang, Sayama, Shirakata, Tokumara, Yahata, Tohyama, Hashimoto: "Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation." in: The Journal of investigative dermatology, Vol. 122, Issue 6, pp. 1356-64, (2004) (PubMed).

Yuan, Xie, Chen: "Depletion of Wee-1 kinase is necessary for both human immunodeficiency virus type 1 Vpr- and gamma irradiation-induced apoptosis." in: Journal of virology, Vol. 77, Issue 3, pp. 2063-70, (2003) (PubMed).

Synonyms and alternative names related to WEE1 Homolog (S. Pombe)

WEE1 G2 checkpoint kinase (WEE1), Wee1 kinase (Wee1), WEE1-like kinase (WEE1), WEE1 G2 checkpoint kinase S homeolog (wee1.S), wee1 homolog (wee1-a), WEE1 homolog 2 (wee2), wee1-like protein kinase (LOC551677), WEE 1 homolog 1 (S. pombe) (Wee1), WEE1 G2 checkpoint kinase (Wee1), M phase inhibitor protein kinase Wee1 (wee1), WEE1 G2 checkpoint kinase (wee1), ATWEE1, F22D16.3, F22D16_3, fa20h03, GB19689, WEE1, wee1, WEE1 kinase homolog, wee1-b, WEE1-KINASE, WEE1A, wee1a, Wee1A, wee1b, WEE1hu, wee1hu, wee2-a, wu:fa20h03, xe-wee1a, Xe-Wee1B, XeWee1B, xwee1, xwee2, zgc:136514

Protein level used designations for WEE1 Homolog (S. Pombe)

  • WEE1+ homolog
  • wee1-like protein kinase
  • wee1A kinase
  • Wee1 kinase
  • Zygotic wee1-like protein kinase 1B
  • wee1-like protein kinase 1-B
  • Wee1A kinase
  • maternally supplied wee1-like protein kinase 1A
  • wee1-like protein kinase 2-A
  • wee1-like protein kinase 2
  • Wee1-like protein kinase
  • WEE1 homolog (S. pombe)
  • WEE1 tyrosine kinase
  • wee1 tyrosine kinase
  • P107 protein kinase homolog
  • WEE1 homolog
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