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抗Human SALL1 抗体:
抗Mouse (Murine) SALL1 抗体:
抗Rat (Rattus) SALL1 抗体:
Dog (Canine) Polyclonal SALL1 Primary Antibody for ELISA - ABIN451618
Wang, Rao, Chu, Shen, Levasseur, Theunissen, Orkin: A protein interaction network for pluripotency of embryonic stem cells. in Nature 2006
Human Polyclonal SALL1 Primary Antibody for ELISA - ABIN4351912
Barry, Reddy: The association of an epibulbar dermoid and Duane syndrome in a patient with a SALL1 mutation (Townes-Brocks Syndrome). in Ophthalmic genetics 2008
Inhibition of SALL1 correlates with reduced levels of CDH1 (显示 CDH1 抗体), an important contributor to epithelial-to-mesenchymal transition.
quantity and quality of SALL1 transcript are important for SALL1 function and determine phenotype, and mode of inheritance, of allelic SALL1-related disorders
report on a family with features of TBS in whom a novel 149 kb deletion spanning the SALL1 gene was identified by high resolution cytogenetics SNP microarray
novel role for Sall1 as a member of the transcriptional network that regulates stem cell pluripotency
Sall1 induces angiogenesis by stimulating VEGF-A (显示 VEGFA 抗体) promoter activity.
Studies indicate that vertebrate sal orthologues (spalt-like/sall) have important developmental roles during neural development and organogenesis and gentic diseases.
Mutation in Townes-Brocks syndrome. Product is a transcriptional repressor which interacts with TRF1/PIN2 (显示 TERF1 抗体) and localizes to pericentromeric heterochromatin.
binding of proteins SALL1, UBE2I (显示 UBE2I 抗体) and SUMO-1 (显示 SUMO1 抗体)
sall1 enhances the canonical Wnt (显示 WNT2 抗体) signaling by localizing to heterochromatin
analysis of SALL1 mutations in Townes-Brocks syndrome
The data of this study indicated that Sall1 regulates microglial morphology during development.
Data suggest that Sall1 is associated with actin reorganization, endoplasmic reticulum stress, and apoptosis in podocytes injured by adriamycin, a topoisomerase II (显示 TOP2 抗体) inhibitor used as antineoplastic antibiotic known to cause nephrosis and glomerulosclerosis.
These findings highlight an important function of Sall1-NuRD interaction in the regulation of Six2 (显示 SIX2 抗体)-positive multipotent renal progenitor cells and formation of the loop of Henle.
this study shows that transcriptional regulation by Sall1 maintains microglial identity and physiological properties in the central nervous system and allows microglia-specific manipulation in vivo
Our study demonstrates that Sall1 marks Cardiac progenitor cells in an undifferentiated state and regulates cardiac differentiation
the expression of Sall1 in stromal progenitors restricts the excessive expansion of nephron progenitors in a non-cell autonomous manner, and Sall1-mediated regulation of Decorin (显示 DCN 抗体) and Fat4 (显示 FAT4 抗体) might at least partially underlie the pathogenesis.
establish a functional role for Sall1 in the response of the adult kidney to acute injury
Dicer (显示 DICER1 抗体) ablation in the early metanephric mesenchyme results in severe renal dysgenesis despite normal initial specification of nephron progenitors and ureteric bud outgrowth.
Sall1 activates progenitor-related genes in Six2 (显示 SIX2 抗体)-positive nephron progenitors and represses gene expression in Six2 (显示 SIX2 抗体)-negative differentiating nascent nephrons.
The findings highlight a novel role for Sall1 in maintaining the stemness of the progenitor cell pool by restraining their differentiation into renal vesicles.
Data show that both sall1 and sall4 (显示 SALL4 抗体) act to repress pou5f3 (oct4)family gene expression in the neural plate, thereby allowing vertebrate neural development to proceed.
The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.
sal-like protein 1
, spalt-like transcription factor 1
, zinc finger protein 794
, zinc finger protein SALL1
, zinc finger protein Spalt-1
, zinc finger protein Spalt-3
, spalt 1
, transcription factor Spalt
, sal-like 1
, sal-like 1 b
, sal-like 1 (Drosophila)