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抗Mouse (Murine) 抗体:
抗Rat (Rattus) 抗体:
Lmo4 participates in the regulation of lung epithelial cell proliferation but is not essential for tumor progression.
LMO4 appears to form a hub in protein-protein interaction networks, linking numerous pathways within cells.
Clim2 (显示 LDB1 抗体), in a complex with LMO4, supports mammary stem cells by directly targeting the Fgfr2 (显示 FGFR2 抗体) promoter in basal cells to increase its expression
Existence of a region in the lateral portion of the mammalian cochlea that is competent to make an organ of Corti is demonstrated in the absence of LMO4 function.
Low LMO4 mRNA levels were associated with response to erlotinib in non-small-cell lung cancer.
oncoprotein HBXIP (显示 HBXIP 抗体) is able to activate the transcriptional coregulatory protein LMO4 through transcription factor Sp1 (显示 SP1 抗体) in promotion of proliferation of breast cancer cells.
Data suggest that overexpression of LMO4 may disrupt some of the normal tumour suppressor activities of CtIP (显示 RBBP8 抗体), thereby contributing to breast cancer progression.
the association of high levels of LMO4 with aggressive neuroblastomas is dependent on LMO4 regulation of cadherin expression and hence, tumor invasiveness
LMO4 is a direct target of p53 (显示 TP53 抗体) and inhibits p53 (显示 TP53 抗体)-mediated proliferative inhibition of breast cancer cells through interacting p53 (显示 TP53 抗体)
LMO4 is over-expressed in highly invasive rhabdomyosarcoma, alveolar cells
Multiple roles of Lmo4 during retinal development.
These results reveal a novel, LMO4-dependent transcriptional program within the basolateral amygdala that is essential to cue-reward learning.
activation of SLK (显示 SLK 抗体) by haptotactic signals requires its recruitment to the leading edge by LMO4 in a Src (显示 SRC 抗体)-dependent manner.
Thus, our study reveals an essential requirement for LMO4 to modulate central insulin (显示 INS 抗体) signaling.
A novel sensory competent region in the lateral cochlear duct is regulated by LMO4.
By increasing neuronal activity in the paraventricular hypothalamus, food intake was suppressed in LMO4-deficient mice.
LMO4 is a novel modulator of adipogenesis.
The results of this study found that LIM domain only 4 (LMO4) inhibits PTP1B (显示 PTPN1 抗体) activity by increasing the oxidized inactive form of PTP1B (显示 PTPN1 抗体) in hypothalamus of mice.
results identify Lmo4 as a central developmental control over the diversity of motor cortex projection neuron subpopulations, establishing their area-specific identity and specialized connectivity.
LMO4 modulates the activity of the DEAF NES (显示 NES 抗体), causing nuclear accumulation of a construct containing the LMO4-interaction region of DEAF1 (显示 DEAF1 抗体).
This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene.
LIM domain only 4
, LIM domain only protein 4
, LIM domain transcription factor LMO4
, breast tumor autoantigen
, ethanol induced 4