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The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 (显示 TAF1 蛋白) recognize the longer butyryl mark on histones. In addition, the TAF1 (显示 TAF1 蛋白) second bromodomain is capable of binding crotonyl marks.
The genes CECR2, SLC25A18 and ATP6V1E1, mapping within the critical region for cat eye syndrome (CES), may be responsible for anorectal, renal and preauricular anomalies in patients with CES.
Cecr2 is important for gamma-H2AX (显示 H2AFX 蛋白) formation and DNA double strand break repair, Cecr2 is a novel DNA damage response protein.
Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis.
cat eye syndrome critical region protein 2
, cat eye syndrome chromosome region, candidate 2
, hypothetical protein LOC799918