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抗Human SLC25A37 抗体:
抗Mouse (Murine) SLC25A37 抗体:
抗Rat (Rattus) SLC25A37 抗体:
RNA-sequencing and Reverse transcriptase PCR showed higher expression of a specific isoform of SLC25A37 in SF3B1 (显示 SF3B2 抗体)-mutant patients, a crucial importer of Fe(2+) into the mitochondria
Compares and contrasts all the known human SLC25A (显示 SLC25A25 抗体)* genes and includes functional information.
Data show that abnormal MFRN1 expression can contribute to erythropoietic protoporphyria (显示 FECH 抗体) phenotype in some patients, probably by causing a reduction in FECH (显示 FECH 抗体) activity.
hypoxia induces the expression of mitoferrin mRNAs through separate mechanisms in erythroid cells
impaired mitochondrial [Fe-S] cluster biogenesis in Mfrn1(gt/gt (显示 FABP6 抗体)) cells results in elevated IRP1 (显示 ACO1 抗体) RNA-binding that attenuates ALAS2 (显示 ALAS2 抗体) mRNA translation and protoporphyrin accumulation
Mitoferrin 1 can cause anemia and protoporphyria (显示 FECH 抗体).
The transcription factor GATA-1 (显示 GATA1 抗体) controls expression of Mitoferrin 1 in development of mammals
Fech (显示 FECH 抗体) forms an oligomeric complex with Mfrn1 and Abcb10 (显示 ABCB10 抗体) to synergistically integrate mitochondrial iron importation and use for heme biosynthesis.
Erythroblasts generated from murine embryonic stem cells null for Mfrn (also known as Slc25a37) show maturation arrest with severely impaired incorporation of 55Fe into haem [mitoferrin]
Mitoferrin 1 and mitoferrin 2 (显示 SLC25A28 抗体) contribute to mitochondrial iron delivery in a variety of cells.
Data show that the binding domain of Mfrn1-Abcb10 (显示 ABCB10 抗体) interaction maps to the N terminus of Mfrn1.
SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009
mitochondrial iron transporter 1
, mitochondrial solute carrier protein
, predicted protein of HQ2217
, solute carrier family 25, member 37
, mitoferrin 1
, mitochondrial carrier domain containing protein RGD1359361
, mitochondrial solute carrier-like protein
, erythroid-specific mitochondrial mitoferrin
, protein frascati
, solute carrier family 25 member 37