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Human S100A8 Protein expressed in Wheat germ - ABIN1319072
Maiseyeu, Badgeley, Kampfrath, Mihai, Deiuliis, Liu, Sun, Parthasarathy, Simon, Croce, Rajagopalan: In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. in Arteriosclerosis, thrombosis, and vascular biology 2012
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Human S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN2181719
Gruda, Ruggeberg, OSullivan, Guliashvili, Scheirer, Golobish, Capponi, Chan: Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads. in PLoS ONE 2017
Mouse (Murine) S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN5569738
Schneider, Schenone, Ferreira, Kramann, Joyce, Hartigan, Beier, Brümmendorf, Germing, Platzbecker, Büsche, Knüchel, Chen, Waters, Chen, Chu, Novina, Lindsley, Carr, Ebert: Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. in Nature medicine 2016
Study found that that the co-stimulation with both advanced glycation end-products and Porphyromonas gingivalis LPS increased S100A8 and S100A9 mRNA expression in gingival epithelial cells. These results demonstrated that the upregulation of calprotectin in gingival epithelial cells may primarily function intracellularly in this tissue and may contribute to the pathological process of periodontitis.
Our results showed that S100A8/A9, absent or present at very low level in skin biopsies from healthy subjects, is dramatically upregulated in each epidermal layer from psoriatic patients.
The results suggest that the calcium-binding proteins S100A8 and S100A9 in myeloid cells have an immune regulatory effect.
Median MRP8/14 levels were higher in patients with Takayasu arteritis.
S100A8 gene knockdown reduced cell proliferation in the HEC-1A cells compared with control cells, induced cell apoptosis, inhibited the phosphorylation of protein kinase B (Akt), and induced the expression of pro-apoptotic genes.
Wide intra- and interindividual differences in calprotectin concentrations in the meconium may reflect intestinal inflammation associated with the fetal adaptation to life outside the uterus.
Salivary calprotectin levels were significantly higher in RAS [Recurrent aphthous stomatitis] group (23.72 +/- 4.28 mg/L) compared to the HC [Healthy Controls] (21.59 +/- 4.27 mg/L) (P = 0.013). No significant relationship was found between calprotectin levels and age or gender in both groups (P >0.05).
the levels of S100A8 and S100A9 in the sera, and calprotectin levels in the sera and urines of bladder cancer patients, were determined.
MRP-8/14 concentration increases in coronary artery blood in association with thrombus formation in acute coronary syndrome.
ANGPTL6, S100A8 and S100A9 are overexpressed in skin of psoriasis patients versus zero expression in controls.
Elevated breast cancer cell and stromal S1008 protein expression are significant indicators of poorer outcomes in early stage breast cancer patients. Evaluation of S100A8 protein expression may provide additional prognostic information beyond traditional breast cancer prognostic biomarkers.
S100A8 was required for laser-induced new collagen synthesis in skin cells.
S100A8 methylation has a role in diagnosis and prognosis of hepatocellular carcinoma
This study demonstrated that S100A8 was detected in the serums of Alzheimer disease patients
Studies indicate S100A8 as the most overexpressed gene, and the cell cycle pathway as the most promising biomarker and therapeutic target for relapsed childhood B-acute lymphoblastic leukemia (B-ALL).
Low S100A8 expression is associated with head and neck neoplasms.
Report role of fecal calprotectin assay in the diagnosis and management of inflammatory bowel disease.
S100A8 and S100A9 aggravate Coxsackievirus B3-induced myocarditis and might serve as therapeutic targets in inflammatory cardiomyopathies.
Data suggest that fecal calprotectin may be a potential biomarker to identify patients with ankylosing spondylitis (AS) at risk of developing inflammatory bowel disease (IBD).
Elevated S100A8 and S100A9 gene expression in SP-infected HMEECs and in the middle ear mucosa of OM, minor co-localized with neutrophil markers suggests that middle ear epithelial cell secretion of S100A8 and S100A9 may play a role in the pathogenesis of recurrent and chronic OM
The findings indicated that plasma concentrations of S100A7 and S100A8 did not change significantly during pregnancy in cows.
study of nonsynonymous DNA variation in the functional domain of the S100A7, -A8, -A9 genes in taurine cattle and yak
Data suggest that up-regulation of S100A8 and S100A9 is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.
Study verified porcine calprotectin (S100A8/A9) expression at the protein level in multiple Haemophilus parasuis infected tissues and explored their molecular characterization.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
, S100 calcium-binding protein A8 (calgranulin A)
, calgranulin A
, calprotectin L1L subunit
, cystic fibrosis antigen
, leukocyte L1 complex light chain
, migration inhibitory factor-related protein 8
, protein S100-A8
, urinary stone protein band A
, S100 calcium binding protein A8 (calgranulin A)
, S100 calcium binding protein A8
, S100 calcium-binding protein A8
, neutrophil cytosolic 7 kDa protein
, chemotactic S100 protein
, chemotactic cytokine CP-10
, pro-inflammatory S100 cytokine
, macrophage migration inhibitory factor-related protein-8