anti-人 TICAM1 抗体 for Western Blotting

Recommended TICAM1 Antibody (supplied by: Log in to see )

抗原
Toll-Like Receptor Adaptor Molecule 1 (TICAM1) 抗体
  • IIAE6
  • MyD88-3
  • PRVTIRB
  • TICAM-1
  • TRIF
  • AW046014
  • AW547018
  • trif
  • toll like receptor adaptor molecule 1
  • toll-like receptor adaptor molecule 1
  • TICAM1
  • Ticam1
  • ticam1
适用
小鼠, 大鼠, 人
83
32
15
4
4
1
1
宿主

77
8
8
克隆类型
多克隆
标记
This TICAM1 antibody is un-conjugated
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
85
32
18
17
13
8
8
4
4
2
1
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see

Available images

产品编号 ABIN3021572
$ 393.25
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
21.123726 ABIN266066 ICC IF IP SimWes WB Rabbit Internal Region Log in to see Polyclonal 27
18.531807 ABIN2855929 ICC IF WB Rabbit IgG C-Term Log in to see Polyclonal 0
16.697172 ABIN1871543 ICC IHC WB Rabbit IgG AA 443-685 Log in to see Polyclonal 0
16.697172 ABIN1875095 IHC WB Rabbit IgG Log in to see Polyclonal 0
16.697172 ABIN2903154 IF/ICC IHC IP WB Rabbit AA 443-685 Log in to see Polyclonal 0
15.197171 ABIN3044491 IHC (fro) IHC (p) WB Rabbit IgG AA 692-712, C-Term Log in to see Polyclonal 1
13.697171 ABIN6265566 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
13.697171 ABIN3029185 IHC (fro) IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal 0
12.197171 ABIN6672552 IHC WB Rabbit IgG Log in to see Polyclonal 1
12.197171 ABIN541214 IHC (p) WB Rabbit Log in to see Polyclonal 3
11.834635 ABIN2613488 ELISA WB Goat Internal Region Log in to see Polyclonal 0
11.834635 ABIN4902391 ELISA WB Rabbit IgG AA 663-712 Log in to see Polyclonal 0
11.834635 ABIN6149149 WB Rabbit Log in to see Polyclonal 0
10 ABIN213993 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
10 ABIN6292306 IHC WB Rabbit IgG Log in to see Polyclonal 0
9.197171 ABIN1881885 WB Rabbit AA 115-143, N-Term Log in to see Polyclonal 5
9.197171 ABIN537469 WB Rabbit Log in to see Polyclonal 3
7.697171 ABIN3223003 IHC WB Rabbit C-Term Log in to see Polyclonal 0
7.697171 ABIN1030771 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
7.697171 ABIN3029184 ELISA WB Rabbit Ig Fraction AA 115-143 Log in to see Polyclonal 0

General

抗原 Toll-Like Receptor Adaptor Molecule 1 (TICAM1) 抗体
适用 小鼠, 大鼠, 人
(83), (32), (15), (4), (4), (1), (1)
宿主
(77), (8), (8)
克隆类型
多克隆
标记 This TICAM1 antibody is un-conjugated
(1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(85), (32), (18), (17), (13), (8), (8), (4), (4), (2), (1), (1)
Pubmed 找到1个引用
Supplier Log in to see

TICAM1抗体详情

TICAM1目标详情 使用细节 贮存及处理 References for anti-TICAM1 antibody (ABIN3021572) 图像
纯化方法 Affinity purification
免疫原 Recombinant protein of human TICAM1
亚型 IgG
Plasmids, Primers & others

TICAM1目标详情

TICAM1抗体详情 使用细节 贮存及处理 References for anti-TICAM1 antibody (ABIN3021572) 图像 回页首
抗原
别名 TICAM1 (TICAM1 Antibody 摘要)
背景 Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. TRIF (also termed TICAM-1) is a TIR-domain adaptor protein described to activate NF-kappaB, IRF3 and trigger IFN-beta production. Studies using dominant negative forms of TRIF and siRNA targeting TRIF show that TRIF functions downstream of both TLR3 and TLR4 in response to dsRNA and LPS respectively. TRIF recruits TRAF6-TAK1-TAB2 to the receptor complex which leads to NF-kappaB activation. In addition, TRIF can trigger signaling of that lead to the induction of apoptosis.
Synonyms: TRIF, PRVTIRB, TICAM-1
基因ID 148022
UniProt Q8IUC6
途径 TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

使用细节

TICAM1抗体详情 TICAM1目标详情 贮存及处理 References for anti-TICAM1 antibody (ABIN3021572) 图像 回页首
应用备注 Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
限制 仅限研究用

贮存及处理

TICAM1抗体详情 TICAM1目标详情 使用细节 References for anti-TICAM1 antibody (ABIN3021572) 图像 回页首
状态 Liquid
缓冲液 PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid freeze / thaw cycles
储存条件 -20 °C/-80 °C

References for anti-TICAM1 antibody (ABIN3021572)

TICAM1抗体详情 TICAM1目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, 2017 Method employed by authors: Western Blotting (WB)

图像

TICAM1抗体详情 TICAM1目标详情 使用细节 贮存及处理 References for anti-TICAM1 antibody (ABIN3021572) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody (ABIN3021572) anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody
Western Blotting (WB) image for anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibody (ABIN3021572) Western blot analysis of extracts of various cell lines, using TICAM1 antibody.