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TAB1 抗体

(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
TAB1 抗体  (AA 205-504) TAB1 抗体  (AA 205-504) TAB1 抗体 (AA 205-504) (ABIN7171965)

TAB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

TAB1 抗体  (AA 3-100) TAB1 抗体  (AA 3-100) TAB1 抗体 (AA 3-100) (ABIN564552)

TAB1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A12 unconjugated

TAB1 抗体  (AA 205-504) TAB1 抗体  (AA 205-504) TAB1 抗体 (AA 205-504) (ABIN6148795)

TAB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

TAB1 抗体 by 适用

Find TAB1 抗体 for a variety of species such as anti-Human TAB1, anti-Mouse TAB1, anti-Rat TAB1. The species listed below are among those available. Click on a link to go to the corresponding products.

TAB1 抗体 by 应用范围

Find TAB1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

TAB1 抗体 by 抗体来源

Find TAB1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TAB1 抗体 by 抗原表位

Find TAB1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TAB1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TAB1 抗体. Click on a link to go to the corresponding products.

TAB1 抗体 by 克隆

Find TAB1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TAB1 抗体 by 标记

Find TAB1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TAB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7171965
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (6)
Cat. No. ABIN564552
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (3)
Cat. No. ABIN6148795
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (1)
Cat. No. ABIN801873
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7241657
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, DB
Validations
  • (3)
  • (1)
Cat. No. ABIN548637
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6263110
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1680832
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN2855576
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6743724
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN523851
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN754348
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
Cat. No. ABIN801875
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), IHC (fro)
Validations
Cat. No. ABIN754350
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5011307
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TAB1 抗体

Hussain, Zhao, Shah, Wang, Yue, Liao, Sabir, Yang, Zhou et al.: "MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 ..." in: Frontiers in immunology, Vol. 8, pp. 1915, (2017) (PubMed).

Sun, Yoshizuka, New, Moser, Li, Liao, Xie, Chen, Deng, Yamout, Dong, Frangou, Yates, Wright, Han: "PRAK is essential for ras-induced senescence and tumor suppression." in: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).

Zhou, Zheng, Chen, Xie, Kolatkar, Zarubin, Ye, Akella, Lin, Goldsmith, Han: "Determinants that control the specific interactions between TAB1 and p38alpha." in: Molecular and cellular biology, Vol. 26, Issue 10, pp. 3824-34, (2006) (PubMed).

Conner, Kular, Peggie, Shepherd, Schüttelkopf, Cohen, Van Aalten: "TAK1-binding protein 1 is a pseudophosphatase." in: The Biochemical journal, Vol. 399, Issue 3, pp. 427-34, (2006) (PubMed).

Singhirunnusorn, Suzuki, Kawasaki, Saiki, Sakurai et al.: "Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex ..." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 7359-68, (2005) (PubMed).

Akira, Takeda: "Toll-like receptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).

Jiang, Ninomiya-Tsuji, Qian, Matsumoto, Li: "Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol." in: Molecular and cellular biology, Vol. 22, Issue 20, pp. 7158-67, (2002) (PubMed).

Irie, Muta, Takeshige: "TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages." in: FEBS letters, Vol. 467, Issue 2-3, pp. 160-4, (2000) (PubMed).

Aliases for TAB1 抗体

TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1) 抗体
TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) 抗体
3'-Tab1 抗体
2310012M03Rik 抗体
b2b449Clo 抗体
MAP3K7IP1 抗体
Map3k7ip1 抗体
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