anti-小鼠 CREB1 抗体 for Intracellular Staining

Recommended CREB1 Antibody

抗原
cAMP Responsive Element Binding Protein 1 (CREB1) 抗体
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
抗原表位
pSer133
131
48
47
29
19
19
16
15
12
10
10
9
8
8
8
7
6
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
622
389
350
42
37
35
33
26
23
22
16
14
13
6
6
6
1
1
1
1
1
宿主
小鼠
553
72
12
1
克隆类型
单克隆
标记
This CREB1 antibody is conjugated to PE
26
15
15
14
13
13
13
13
13
8
7
6
3
3
3
3
3
1
应用范围
Intracellular Staining (ICS)
453
270
224
96
84
57
42
40
27
18
11
10
5
3
2
2
1
1
选项

Available images

产品编号 ABIN1177047
产品在该地区无法提供。
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
8.5 ABIN1177048 ICS Alexa Fluor 647 Mouse IgG1, kappa pSer133 J151-21 1
8.5 ABIN1177049 ICS Alexa Fluor 488 Mouse IgG1, kappa pSer133 J151-21 1

General

抗原 cAMP Responsive Element Binding Protein 1 (CREB1) 抗体
抗原表位 pSer133
(131), (48), (47), (29), (19), (19), (16), (15), (12), (10), (10), (9), (8), (8), (8), (7), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(622), (389), (350), (42), (37), (35), (33), (26), (23), (22), (16), (14), (13), (6), (6), (6), (1), (1), (1), (1), (1)
宿主 小鼠
(553), (72), (12), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This CREB1 antibody is conjugated to PE
(26), (15), (15), (14), (13), (13), (13), (13), (13), (8), (7), (6), (3), (3), (3), (3), (3), (1)
应用范围 Intracellular Staining (ICS)
(453), (270), (224), (96), (84), (57), (42), (40), (27), (18), (11), (10), (5), (3), (2), (2), (1), (1)
Pubmed 找到1个引用
Supplier

CREB1抗体详情

CREB1目标详情 使用细节 贮存及处理 References for anti-CREB1 antibody (ABIN1177047) 图像
品牌 BD Phosflow™
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Phosphorylated Human CREB Peptide
克隆位点 J151-21
亚型 IgG1, kappa
Plasmids, Primers & others

CREB1目标详情

CREB1抗体详情 使用细节 贮存及处理 References for anti-CREB1 antibody (ABIN1177047) 图像 回页首
抗原
别名 CREB (CREB1 Antibody 摘要)
背景 Transcription of various genes is regulated by the cyclic AMP (cAMP) signal transduction pathway through a family of cAMP Responsive Element (CRE)-Binding transcription factors that include CREB, CREM (CRE Modulator), and ATF-1 (Activating Transcription Factor 1). The genes for these transcription factors encode multiple isoforms that are created by alternative splicing, alternative initiation codons, and alternative intronic promoters. Homo- and heterodimers of these members of the basic domain-and-leucine zipper superfamily of proteins bind the palindromic TGACGTCA sequence of CRE. CREB is expressed in all somatic cells, and many different stimuli activate CREB by phosphorylation of its serine 133 (S133). The transcriptional activity and specificity of CREB are regulated by the signaling pathways initiated by the various stimuli. Transcriptional regulation by CREB family members has been implicated in many physiological responses to extracellular and environmental stimuli, such as memory, tissue growth and development, and homeostasis. The J151-21 monoclonal antibody recognizes the phosphorylated S133 of human CREB in addition to cross-reacting with S63 of human ATF-1.
途径 TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

使用细节

CREB1抗体详情 CREB1目标详情 贮存及处理 References for anti-CREB1 antibody (ABIN1177047) 图像 回页首
样本量 20 μL
限制 仅限研究用

贮存及处理

CREB1抗体详情 CREB1目标详情 使用细节 References for anti-CREB1 antibody (ABIN1177047) 图像 回页首
状态 Liquid
缓冲液 Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

References for anti-CREB1 antibody (ABIN1177047)

CREB1抗体详情 CREB1目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Shaywitz, Greenberg: "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals." in: Annual review of biochemistry, Vol. 68, Issue 2, pp. 821-61, 2000

图像

CREB1抗体详情 CREB1目标详情 使用细节 贮存及处理 References for anti-CREB1 antibody (ABIN1177047) 回页首
厂商提供的图像
Flow Cytometry (FACS) image for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (PE) (ABIN1177047) anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (PE)