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LRP2 蛋白

(Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].
LRP2 Protein (AA 4447-4655) (His tag) LRP2 Protein (AA 4447-4655) (His tag) LRP2 Protein (AA 4447-4655) (His tag) (ABIN3083291)

Crystallography grade LRP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

LRP2 Protein (AA 4447-4660) (His tag) LRP2 Protein (AA 4447-4660) (His tag) LRP2 Protein (AA 4447-4660) (His tag) (ABIN3130822)

Crystallography grade LRP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

LRP2 Protein (AA 4035-4184) (His tag) (ABIN7397174)

LRP2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC

LRP2 蛋白 by Grade

Find LRP2 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LRP2 蛋白 by Origin

Find LRP2 蛋白 for a variety of species such as anti-Human LRP2, anti-Mouse LRP2. The species listed below are among those available. Click on a link to go to the corresponding products.

LRP2 蛋白 by Source

Here you will find LRP2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LRP2 蛋白 by 蛋白类型

Here you can find LRP2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

LRP2 蛋白 by 应用范围

Find LRP2 蛋白 validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular LRP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083291
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130822
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397174
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713618
Quantity 100 μg
Datasheet Datasheet

Aliases for LRP2 蛋白

LDL receptor related protein 2 (LRP2) 蛋白
low density lipoprotein receptor-related protein 2a (lrp2a) 蛋白
low density lipoprotein receptor-related protein 2 (LRP2) 蛋白
low-density lipoprotein receptor-related protein 2 (LRP2.3) 蛋白
LDL receptor related protein 2 L homeolog (lrp2.L) 蛋白
low-density lipoprotein receptor-related protein 2 (LOC100183506) 蛋白
LDL receptor related protein 2 (lrp2) 蛋白
low density lipoprotein receptor-related protein 2 (Lrp2) 蛋白
LDL receptor related protein 2 (Lrp2) 蛋白
AI315343 蛋白
AW536255 蛋白
D230004K18Rik 蛋白
dbs 蛋白
DBS 蛋白
gp330 蛋白
GP330 蛋白
Gp330 蛋白
im:680590 蛋白
lrp2 蛋白
megalin 蛋白
Megalin 蛋白
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