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VAV1 抗体

(Vav 1 Oncogene (VAV1))
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].
VAV1 抗体  (AA 121-324) VAV1 抗体  (AA 121-324) VAV1 抗体 (AA 121-324) (ABIN969581)

VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2-00E-11 unconjugated

VAV1 抗体  (AA 565-795) VAV1 抗体  (AA 565-795) VAV1 抗体 (AA 565-795) (ABIN7444313)

VAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

VAV1 抗体  (pTyr174) VAV1 抗体  (pTyr174) VAV1 抗体 (pTyr174) (ABIN6256653)

VAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

VAV1 抗体 by 适用

Find VAV1 抗体 for a variety of species such as anti-Human VAV1, anti-Rat VAV1, anti-Mouse VAV1. The species listed below are among those available. Click on a link to go to the corresponding products.

VAV1 抗体 by 应用范围

Find VAV1 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

VAV1 抗体 by 抗体来源

Find VAV1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

VAV1 抗体 by 抗原表位

Find VAV1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

VAV1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal VAV1 抗体. Click on a link to go to the corresponding products.

VAV1 抗体 by 克隆

Find VAV1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

VAV1 抗体 by 标记

Find VAV1 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular VAV1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (5)
Cat. No. ABIN969581
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7444313
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN6256653
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN563363
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN521299
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265950
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2855640
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7180104
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7271302
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014526
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138948
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6744384
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3187609
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN711881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
Cat. No. ABIN7182955
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our VAV1 抗体

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Bertagnolo, Nika, Brugnoli, Bonora, Grassilli, Pinton, Capitani: "Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells." in: Cell and tissue research, Vol. 345, Issue 1, pp. 163-75, (2011) (PubMed).

Yin, Wan, Li, Du, Zhang, Zhou, Cao: "The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells." in: Acta pharmacologica Sinica, Vol. 32, Issue 1, pp. 99-107, (2011) (PubMed).

Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7966-74, (2009) (PubMed).

Amarasinghe, Rosen: "Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain." in: Biochemistry, Vol. 44, Issue 46, pp. 15257-68, (2005) (PubMed).

Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, (2005) (PubMed).

Miura-Shimura, Duan, Rao, Reddi, Shimura, Rottapel, Druker, Tsygankov, Band, Band: "Cbl-mediated ubiquitinylation and negative regulation of Vav." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38495-504, (2003) (PubMed).

Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, (2000) (PubMed).

Aliases for VAV1 抗体

vav guanine nucleotide exchange factor 1 (VAV1) 抗体
vav guanine nucleotide exchange factor 1 (Vav1) 抗体
vav 1 oncogene (Vav1) 抗体
vav guanine nucleotide exchange factor 1 L homeolog (vav1.L) 抗体
VAV 抗体
Vav 抗体
vav-T 抗体
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