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HLA-DRB5 蛋白

(Major Histocompatibility Complex, Class II, DR beta 5 (HLA-DRB5))
HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
HLA-DRB5 Protein (AA 30-227) (His tag) HLA-DRB5 Protein (AA 30-227) (His tag) HLA-DRB5 Protein (AA 30-227) (His tag) (ABIN3092198)

Crystallography grade HLA-DRB5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

HLA-DRB5 Protein (AA 30-266) (rho-1D4 tag) HLA-DRB5 Protein (AA 30-266) (rho-1D4 tag) HLA-DRB5 Protein (AA 30-266) (rho-1D4 tag) (ABIN3115191)

Crystallography grade HLA-DRB5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

HLA-DRB5 蛋白 by Grade

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HLA-DRB5 蛋白 by Origin

Find HLA-DRB5 蛋白 for a variety of species such as anti-Human HLA-DRB5. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB5 蛋白 by Source

Here you will find HLA-DRB5 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-DRB5 蛋白 by 蛋白类型

Here you can find HLA-DRB5 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-DRB5 蛋白 by 应用范围

Find HLA-DRB5 蛋白 validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-DRB5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3092198
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3115191
Quantity 1 mg
Datasheet Datasheet

Aliases for HLA-DRB5 蛋白

major histocompatibility complex, class II, DR beta 5 (HLA-DRB5) 蛋白
HLA-DRB 蛋白
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