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PSMB8 抗体

(Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified\; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008].
PSMB8 抗体  (AA 173-272) PSMB8 抗体  (AA 173-272) PSMB8 抗体 (AA 173-272) (ABIN562483)

PSMB8 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated

PSMB8 抗体 PSMB8 抗体 PSMB8 抗体 (ABIN969371)

PSMB8 适用: 人, 大鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1A5 unconjugated

PSMB8 抗体  (AA 75-261) PSMB8 抗体  (AA 75-261) PSMB8 抗体 (AA 75-261) (ABIN7440236)

PSMB8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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Find PSMB8 抗体 for a variety of species such as anti-Human PSMB8, anti-Rat PSMB8, anti-Mouse PSMB8. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular PSMB8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IF, IHC (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN562483
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, ELISA, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN969371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7440236
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7440308
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7440281
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (4)
Cat. No. ABIN519382
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7263353
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ICC, IHC (p)
Validations
  • (4)
Cat. No. ABIN2856915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7192036
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN519381
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7164990
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN571001
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7307018
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN680833
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN680835
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PSMB8 抗体

Hamamura, Chen, Nishimura, Tanjung, Sudo, Yokota: "Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis." in: Cellular signalling, Vol. 26, Issue 11, pp. 2358-69, (2014) (PubMed).

Nijholt, de Graaf, van Haastert, Oliveira, Berkers, Zwart, Ovaa, Baas, Hoozemans, Scheper: "Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 1071-81, (2011) (PubMed).

Camarena, Aquino-Galvez, Falfán-Valencia, Sánchez, Montaño, Ramos, Juárez, García-de-Alba, Granados, Selman: "PSMB8 (LMP7) but not PSMB9 (LMP2) gene polymorphisms are associated to pigeon breeder's hypersensitivity pneumonitis." in: Respiratory medicine, Vol. 104, Issue 6, pp. 889-94, (2010) (PubMed).

Meister, Frey, Lang, Gaipl, Schett, Schlötzer-Schrehardt, Voll: "Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 7, pp. 550-61, (2010) (PubMed).

Lang, Mielenz, Neubert, Böhm, Schett, Jäck, Voll, Meister: "The early marginal zone B cell-initiated T-independent type 2 response resists the proteasome inhibitor bortezomib." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 5637-47, (2010) (PubMed).

Mehta, Jordanova, Corver, van Wezel, Uh, Kenter, Jan Fleuren: "Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma." in: Genes, chromosomes & cancer, Vol. 48, Issue 5, pp. 410-8, (2009) (PubMed).

Deshpande, Wheeler, Hunt, Peyton, White, Valdez, Nolan: "Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer." in: The Journal of infectious diseases, Vol. 197, Issue 3, pp. 371-81, (2008) (PubMed).

Schwarz, van Den Broek, Kostka, Kraft, Soza, Schmidtke, Kloetzel, Groettrup: "Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 2, pp. 768-78, (2000) (PubMed).

Aliases for PSMB8 抗体

proteasome subunit beta 8 (PSMB8) 抗体
proteasome subunit beta 8A (psmb8a) 抗体
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8) 抗体
proteasome subunit beta 8 (Psmb8) 抗体
ALDD 抗体
ATP6V0D2 抗体
D6S216 抗体
D6S216E 抗体
JMP 抗体
Lmp-7 抗体
LMP7 抗体
lmp7 抗体
Lmp7 抗体
macropain 抗体
NKJO 抗体
prosome 抗体
PSMB5i 抗体
RING10 抗体
Ring10 抗体
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