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抗Human TRIM9 抗体:
抗Mouse (Murine) TRIM9 抗体:
抗Rat (Rattus) TRIM9 抗体:
Human Monoclonal TRIM9 Primary Antibody for ELISA, WB - ABIN566708
Shi, Cho, Inn, Yang, Zhao, Liang, Versteeg, Amini-Bavil-Olyaee, Wong, Zlokovic, Park, García-Sastre, Jung: Negative regulation of NF-?B activity by brain-specific TRIpartite Motif protein 9. in Nature communications 2014
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topographic separation of the presynaptic terminals of adjacent nociceptive neurons requires different levels of Trim9, an evolutionarily conserved signaling molecule
TRIM9s undergoes Lys (显示 LYZ 抗体)-63-linked auto-polyubiquitination and serves as a platform to bridge GSK3beta (显示 GSK3b 抗体) to TBK1 (显示 TBK1 抗体), leading to the activation of IRF3 (显示 IRF3 抗体) signaling.
Authors demonstrate that tripartite motif protein 9 (TRIM9)-dependent ubiquitination of DCC (显示 DCC 抗体) blocks the interaction with and phosphorylation of FAK (显示 PTK2 抗体).
TRIM9 is a brain-specific (显示 CALY 抗体) negative regulator of the NF-kappaB (显示 NFKB1 抗体) pro-inflammatory signalling pathway.
These results suggest that TRIM9 plays an important role in the regulation of neuronal functions and participates in pathological process of Lewy body disease through its ligase activity.
Trim9 mediates cellular movement and migration in macrophages as well as neurons.
Adult-born dentate granule cells lacking Trim9 exhibited excessive dendritic arborization and mislocalization of cell bodies in vivo
a gradient of TRIM9-mediated ubiquitination of VASP (显示 VASP 抗体) creates a filopodial stability gradient during axon turning
TRIM9 is expressed in the mouse embryonic and adult nervous system
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.
tripartite motif-containing 9
, tripartite motif containing 9
, anomalies in sensory axon patterning
, tripartite motif protein 9
, E3 ubiquitin-protein ligase TRIM9
, RING finger protein 91
, homolog of rat RING finger Spring
, tripartite motif-containing protein 9
, SNAP-25-interacting RING finger protein