anti-小鼠 Neurexin 1 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Neurexin 1 Antibody

抗原
Neurexin 1 (NRXN1) 抗体
  • Hs.22998
  • PTHSL2
  • SCZD17
  • CG7050
  • CT21808
  • Dmel\\CG7050
  • Nrx
  • Nrx1
  • dnrx
  • dnrx-1
  • nrx
  • Nrxn1b
  • NRXN1
  • Nrx-1
  • GB13455
  • GB18754
  • 1700062G21Rik
  • 9330127H16Rik
  • A230068P09Rik
  • mKIAA0578
  • neurexin 1
  • Neurexin 1
  • neurexin I
  • neurexin 1b
  • NRXN1
  • Nrx-1
  • Nrxn1
  • nrxn1
  • nrxn1b
抗原表位
AA 40-90
16
15
4
3
2
2
2
2
2
1
1
适用
人, 小鼠, 大鼠
77
36
33
4
3
1
宿主

55
20
5
2
2
克隆类型
多克隆
标记
非结合性
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
41
13
11
5
3
3
2
1
1
1
选项

Available images

产品编号 ABIN1386379
$ 317.90
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN1409330 IHC (p) WB HRP Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1391437 IHC (p) WB Biotin Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1387438 IF (p) IHC (p) WB Rabbit IgG AA 280-330 Polyclonal 0

General

抗原 Neurexin 1 (NRXN1) 抗体
抗原表位 AA 40-90
(16), (15), (4), (3), (2), (2), (2), (2), (2), (1), (1)
适用 人, 小鼠, 大鼠
(77), (36), (33), (4), (3), (1)
宿主
(55), (20), (5), (2), (2)
克隆类型
多克隆
标记 非结合性
(4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (41), (13), (11), (5), (3), (3), (2), (1), (1), (1)
Supplier

产品细节

目标详细情况 使用细节 贮存及处理 图像
纯化方法 Purified by Protein A.
免疫原 KLH conjugated synthetic peptide derived from human Neurexin 1
亚型 IgG

目标详细情况

产品细节 使用细节 贮存及处理 图像 回页首
抗原
别名 Neurexin 1 (NRXN1 Antibody 摘要)
背景

Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.

Subcellular location: Extracellular

Synonyms: Neurexin 1 alpha, Neurexin 1 beta, Neurexin I-alpha, Neurexin-1-alpha, NRX1A_HUMAN, NRXN1, PTHSL2.

基因ID 9378
UniProt Q9ULB1
途径 Synaptic Membrane, Skeletal Muscle Fiber Development

使用细节

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应用备注 WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
限制 仅限研究用

贮存及处理

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状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20°C
有效期 12 months

图像

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厂商提供的图像
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Neurexin 1 (NRXN1) (AA 40-90) antibody (ABIN1386379) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Neurexin 1 Po...