anti-ETV5 (ETV5) 抗体产品概述

Human Ets Variant 5 (ETV5) interaction partners

1. exploration of the underlying mechanism demonstrated that ICAM3 (显示 ICAM3 抗体) not only binds to LFA-1 (显示 ITGAL 抗体) with its extracellular domain and structure protein ERM but also to lamellipodia with its intracellular domain which causes a tension that pulls cells apart (metastasis).

2. High Etv5 expression is associated with glioma.

3. four oncogenic ETS (显示 ETS1 抗体) (ERG (显示 ERG 抗体), ETV1 (显示 ETV1 抗体), ETV4 (显示 ETV4 抗体), and ETV5), and no other ETS (显示 ETS1 抗体), interact with the Ewing's sarcoma breakpoint protein, EWS (显示 EWSR1 抗体).

4. Novel ETV5 SNP rs7647305 is associated with childhood hypertension adjusted by obesity.

5. Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETV1 (显示 ETV1 抗体), ETV4 (显示 ETV4 抗体) and ETV5.

6. the prostate cancer-related oncogenic E26 transformation-specific (ETS (显示 ETS1 抗体)) transcription factors, ETV1 (显示 ETV1 抗体), ETV4 (显示 ETV4 抗体), and ETV5, were required for TAZ (显示 TAZ 抗体) gene transcription in PC3 (显示 PCSK1 抗体) prostate cancer cells

7. MiR (显示 MLXIP 抗体)-200b inhibition by transfection in MCF-7 markedly decreased miR (显示 MLXIP 抗体)-200b level, elevated ERM expression, and enhanced cell migration and invasion. MiR (显示 MLXIP 抗体)-200b overexpression in MDA-MB-231 obviously increased miR (显示 MLXIP 抗体)-200b level, reduced ERM expression, and weakened cell migration and invasion.

8. Resistin (显示 RETN 抗体), a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation

9. ERM proteins contribute toward accelerated CD44 (显示 CD44 抗体) shedding by MT1-MMP (显示 MMP14 抗体) through ERM protein-mediated interactions between their cytoplasmic tails.

10. Our results reveal a novel ERM-based spatial mechanism that is coopted by DLBCL cells to sustain tumor cell growth and survival.

Zebrafish Ets Variant 5 (ETV5) interaction partners

1. etv5a and etv4 (显示 ETV4 抗体) have roles in mediating epithelial cell fate during zebrafish kidney development

2. Zebrafish etv5a is essential for the inhibition of ventral mesoderm cell proliferation and for the formation of the hemato-vascular lineage.

Mouse (Murine) Ets Variant 5 (ETV5) interaction partners

1. ETV5 regulates ductal morphogenesis with Sox9 (显示 SOX9 抗体) and is critical for regeneration from pancreatitis

2. High Etv5 expression is associated with glioma.

3. This study demonstrates that Etv4 (显示 ETV4 抗体) and Etv5 transcription factors are expressed in hippocampal pyramidal neurons during the main period of dendritogenesis; reveals a novel role for Etv4 (显示 ETV4 抗体) and Etv5 transcription factors for hippocampal circuit development and the coordination of synaptic maturation; and indicates that both factors are essential in the transcriptional program linking BDNF (显示 BDNF 抗体) signaling to dendrite development.

4. Etv5 is expressed alveolar type II cells in adult lung.Etv5 is a critical output of Ras signaling in alveolar type II cells, contributing to both lung homeostasis and tumor initiation.

5. SOX9 (显示 SOX9 抗体) regulation of ETV5 contributes to the control of male fertility

6. this study shows that Etv5 plays a crucial role in regulating IL-10 (显示 IL10 抗体) production in Th2 cells by facilitating the binding of IL-10 (显示 IL10 抗体)-inducing transcription factors at the Il10 (显示 IL10 抗体) locus

7. findings demonstrate that ETV5 promotes IL-9 production in Th9 cells by binding and recruiting histone acetyltransferases to the Il9 locus at sites distinct from PU.1. data define a role for ETV5 in Th9 development and extend the paradigm of related transcription factors having complementary functions during differentiation

8. substrate that mediates RFWD2 function in lung branching

9. bioinformatic analysis, real-time PCR, and luciferase assay validated that AK015322 serves as a decoy of microRNA-19b-3p (miR (显示 MLXIP 抗体)-19b-3p), antagonizes its function, and attenuates the repression of its endogenous target transcriptional factor Ets-variant 5 (ETV5) which was a pivotal gene for spermatogonial stem cell self-renewal

10. Further investigations identified Pak1 (显示 PAK1 抗体)-ERM as a downstream signaling cascade upon Rac1 (显示 RAC1 抗体) activation in the luminal epithelium necessary for uterine receptivity...Rac1 (显示 RAC1 抗体) via P38 MAPK (显示 MAPK14 抗体) signaling ensures timely epithelial apoptotic death at postimplantation.