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Human CX3CL1 Protein expressed in Escherichia coli (E. coli) - ABIN803628
Yoong, Too: Glial cell line-derived neurotrophic factor and neurturin inhibit neurite outgrowth and activate RhoA through GFR alpha 2b, an alternatively spliced isoform of GFR alpha 2. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
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Human CX3CL1 Protein expressed in - ABIN621641
Kim, Rooper, Xie, Kajdacsy-Balla, Barbolina: Fractalkine receptor CX(3)CR1 is expressed in epithelial ovarian carcinoma cells and required for motility and adhesion to peritoneal mesothelial cells. in Molecular cancer research : MCR 2012
Human CX3CL1 Protein expressed in Human Cells - ABIN2003167
Bazan, Bacon, Hardiman, Wang, Soo, Rossi, Greaves, Zlotnik, Schall: A new class of membrane-bound chemokine with a CX3C motif. in Nature 1997
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that CX3CL1-CX3CR1 (显示 CX3CR1 蛋白) signaling is a molecular mechanism capable of modulating microglial-mediated degeneration
CXCR4 (显示 CXCR4 蛋白)(+) CD45 (显示 PTPRC 蛋白)(-) bone marrow cells are niche forming for osteoclastogenesis via the SDF-1 (显示 CXCL12 蛋白), CXCL7 (显示 PPBP 蛋白), and CX3CL1 signaling pathways in bone marrow.
Increased fractalkine and its receptor CX3CR1 (显示 CX3CR1 蛋白) may cause a cross-talk between activated glial cells and neurons, playing an important role in the development of neuroinflammation in fructose-fed mice.
miR (显示 MLXIP 蛋白)-223 controls the expression of CX3CL1 by targeting HDAC2 (显示 HDAC2 蛋白) in chronic obstructive pulmonary disease patients and mouse models of the disease.
in this study, CX3CL1 is identified as a novel substrate of MMP-19 (显示 MMP19 蛋白)
The CX3CL1/CX3CR1 (显示 CX3CR1 蛋白) system is essential for restricting coxsackievirus B3-induced myocarditis.
changes in GSK-3beta activity and/or levels regulate the production and subsequent secretion of fractalkine, a chemokine (显示 CCL1 蛋白) involved in the immune response that has been linked to AD and to other different neurological disorders.
the individual and combined actions of CCL2 (显示 CCL2 蛋白)/CCR2 (显示 CCR2 蛋白) and CX3CL1/CX3CR1 (显示 CX3CR1 蛋白) in hypoxia-induced pulmonary hypertension in mice, is reported.
Medial ganglionic eminence (MGE) interneurons secrete fractalkine that promotes genesis of oligodendrocytes from glially biased cortical precursors in culture. Moreover, when MGE interneurons are genetically ablated in vivo prior to their migration, this causes a deficit in cortical oligodendrogenesis.
our findings reveal a previously unknown regulatory role for LRRK2 (显示 LRRK2 蛋白) in CX3CR1 (显示 CX3CR1 蛋白) signalling and suggest that an increase of CX3CR1 (显示 CX3CR1 蛋白) activity contributes to the attenuated inflammatory responses in Lrrk2 (显示 LRRK2 蛋白)-null microglia
CX3CL1/CX3CR1 (显示 CX3CR1 蛋白) axis plays a key role in the development of ischemia-induced oligodendrocyte injury via p38MAPK (显示 MAPK14 蛋白) signaling pathway.
high levels of fractalkine in ectopic endometrium taken from patients with endometriosis promoted proliferation and invasion of endometrial stromal cells through activating AKT (显示 AKT1 蛋白) and p38 (显示 CRK 蛋白) signal pathways
Amendment of the cytokine profile in macrophages subsequent to their interaction with smooth muscle cells: Differential modulation by fractalkine and resistin (显示 RETN 蛋白).
Soluble FKN that was efficiently shed from the surface of LPS (显示 IRF6 蛋白)-activated ECs in response to binding of CD16 (显示 CD16 蛋白)(+) monocytes to ECs, diminished monocyte adhesion in down-regulating CX3CR1 (显示 CX3CR1 蛋白) expression on the surface of CD16 (显示 CD16 蛋白)(+) monocytes resulting in decreased TNF (显示 TNF 蛋白)-secretion.
Data indicate that patients with systemic sclerosis (SSc (显示 CYP11A1 蛋白)) displayed higher serum levels of VEGF (显示 VEGFA 蛋白), endothelin-1 (显示 EDN1 蛋白) and s-Fractalkine, and that the s-Fractalkine levels positively correlated with CD34 (显示 CD34 蛋白)(+)CD45 (显示 PTPRC 蛋白)(-) endothelial progenitor cells (EPC (显示 TCF21 蛋白)) numbers.
FKN and CX3CR1 (显示 CX3CR1 蛋白) expression was significantly increased in pancreatic ductal adenocarcinoma (PDAC) tissues, especially in the metastatic samples, and was highly-correlated with severity of PDAC. Ectopic expression of FKN promoted the proliferation and migration of PDAC, while knockdown of CX3CR1 (显示 CX3CR1 蛋白) reversed the function of FKN.
Fractalkine may be involved in both immunopathological and anti-viral immune responses to rhinovirus infection in asthma.
High CX3CL1 expression is associated with spinal metastases.
High expression of CX3CR1 (显示 CX3CR1 蛋白) correlates with significantly shorter survival, specifically in post-menopausal patients with advanced and terminal stages of the disease. Taken together, this support a key regulatory role for the fractalkine axis in advanced and relapsed peritoneal metastasis in epithelial ovarian carcinoma.
Chemotactic factor. Binds to CX3CR1.
, chemokine (C-X3-C motif) ligand 1
, chemokine (C-X3-C motif) ligand 1, related sequence 1
, small inducible cytokine subfamily D, 1-related sequence 1
, CX3CL1 chemokine
, C-X3-C motif chemokine 1
, CX3C membrane-anchored chemokine
, small inducible cytokine subfamily D, 1
, small-inducible cytokine D1
, small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
, small inducible cytokine subfamily D (Cys-X3-Cys), member-1