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CHRNA7 蛋白

(Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) (ABIN7122359)

CHRNA7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

CHRNA7 Protein (AA 318-469) (His tag) CHRNA7 Protein (AA 318-469) (His tag) CHRNA7 Protein (AA 318-469) (His tag) (ABIN3088463)

Crystallography grade CHRNA7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

CHRNA7 Protein (AA 23-230) (His tag) CHRNA7 Protein (AA 23-230) (His tag) CHRNA7 Protein (AA 23-230) (His tag) (ABIN3088462)

Crystallography grade CHRNA7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

CHRNA7 蛋白 by Grade

Find CHRNA7 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CHRNA7 蛋白 by Origin

Find CHRNA7 蛋白 for a variety of species such as anti-Human CHRNA7, anti-Mouse CHRNA7, anti-Rat CHRNA7. The species listed below are among those available. Click on a link to go to the corresponding products.

CHRNA7 蛋白 by Source

Here you will find CHRNA7 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CHRNA7 蛋白 by 蛋白类型

Here you can find CHRNA7 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CHRNA7 蛋白 by 应用范围

Find CHRNA7 蛋白 validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CHRNA7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122359
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088463
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088462
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134257
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134255
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113499
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134256
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN7508493
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413079
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424392
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750643
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our CHRNA7 蛋白

Chandley, Miller, Kwasigroch, Wilson, Miller: "Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia." in: Schizophrenia research, Vol. 109, Issue 1-3, pp. 98-101, (2009) (PubMed).

Aliases for CHRNA7 蛋白

cholinergic receptor nicotinic alpha 7 subunit (CHRNA7) 蛋白
neuronal acetylcholine receptor subunit alpha-7 (LOC100374356) 蛋白
cholinergic receptor, nicotinic, alpha 7 (neuronal) (chrna7) 蛋白
cholinergic receptor, nicotinic, alpha polypeptide 7 (Chrna7) 蛋白
cholinergic receptor nicotinic alpha 7 subunit (Chrna7) 蛋白
cholinergic receptor, nicotinic, alpha 7 (CHRNA7) 蛋白
neuronal acetylcholine receptor subunit alpha-7 (LOC100060521) 蛋白
Acra7 蛋白
alpha7 蛋白
BTX 蛋白
CHRNA7 蛋白
CHRNA7-2 蛋白
dZ70B1.1 蛋白
NACHRA7 蛋白
nAChRa7 蛋白
NARAD 蛋白
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