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Dog (Canine) Polyclonal SULT1E1 Primary Antibody for WB - ABIN2783458
Yalcin, More, Neira, Lu, Cherrington, Slitt, King: Downregulation of sulfotransferase expression and activity in diseased human livers. in Drug metabolism and disposition: the biological fate of chemicals 2013
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Human Polyclonal SULT1E1 Primary Antibody for WB - ABIN233862
Cole, Keum, Liu, Small, Satyamurthy, Kepe, Barrio: Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates. in Proceedings of the National Academy of Sciences of the United States of America 2010
These results suggest that the availability of estrogens in the boar epididymis may be locally controlled also by steroid sulphatase (显示 STS 抗体) and estrogen sulphotransferase.
These results resolve the conflicting results on the localization of SULT1E1 from earlier studies and suggest that posttranscriptional mechanisms play an important role in the control of SULT1E1 expression during TGC (显示 TGM2 抗体) differentiation.
the activities of free estrogens produced in bovine TGC are curtailed by SULT1E1 expressed in UTC and in fetal liver
Our study shows that estrogen sulfotransferase is present in both the intracellular and intraluminal compartments of the epididymis, suggesting that this enzyme plays different roles along the excurrent duct.
A crucial adipose- and male-specific role of Est (显示 MAP3K8 抗体) in maintaining the whole-body energy homeostasis.
Gene profiling identifies sulfotransferase family 1E (Sult1e1), which encodes a sulfotransferase E1 responsible for inactivation of estrogen, as a gene upregulated in non-alcoholic steatohepatitis in both genders and most conspicuously in male IkbkbDeltahep mice having worst non-alcoholic steatohepatitis and lowest plasma estradiol levels.
The role of estrogen sulfotransferase, a conjugating enzyme that sulfonates and deactivates estrogens, in sepsis response is reported.
Liver ischemia and reperfusion (I/R) induced the expression of EST (显示 MAP3K8 抗体) and comprised estrogen activity in an Nrf2 (显示 NFE2L2 抗体)-dependent manner. EST (显示 MAP3K8 抗体) ablation gender-specifically affected I/R sensitivity.
EST (显示 MAP3K8 抗体) functions as a negative regulator of adipogenesis.
Murine SULT1E1 inhibition in vitro and in silico was investigated and compared this to data for the human enzyme.
results suggest that estrogen sulfotransferase plays a physiologic role in protecting Leydig cells from estrogen-induced biochemical lesions
Data show that ablation of the mouse estrogen sulfotransferase gene Sult1e1 causes placental thrombosis and spontaneous fetal loss.
estrogen sulfotransferase, the enzyme that inactivates estrogen, has been found selectively expressed in male tissues, thus suggesting a role for this enzyme to protect male-specific tissues against estrogenic activity
Elevated SULT1E1 levels and associated alterations in estrogen-regulated hepatic protein expression may play an important role in cystic fibrosis (显示 S100A8 抗体) liver disease
Single nucleotide polymorphisms in SULT1E1 were significantly associated with time to treatment failure in men on abiraterone acetate therapy. The single nucleotide polymorphisms may serve as predictive markers for treatment with abiraterone acetate.
Resveratrol and all its derivatives reduced also SULT1E1 mRNA transcript level. The reduced expression of AhR (显示 AHR 抗体), CYP1A1 (显示 CYP1A1 抗体), and 1B1 was also found as a result of treatment with these compounds.
Data show that both estrogen sulfatase (STS) and estrogen sulfotransferase (EST) were highly expressed in the human umbilical vein
Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase (显示 STS 抗体) expression in endometriosis tissue and stromal cells
a model that enables prediction of substrates and inhibitors of SULT1E1, is reported.
Data suggest that the substrate specificities of SULT1E1 and SULT1A1 (显示 SULT1A1 抗体)*1 include metabolites of tamoxifen (endoxifen, 4-hydroxytamoxifen, and N-desmethyltamoxifen); these metabolites are weak inhibitors of sulfation of estradiol by SULT1E1/SULT1A1 (显示 SULT1A1 抗体)*1.
Authors propose that the formation of this DNA loop and protein-bound complex prevents additional binding of ETS1 (显示 ETS1 抗体) and p53 (显示 TP53 抗体) R273H proteins to other proximal binding sites.
Data indicate that protein-ligand interaction energy by using docking Quantitative Structure-Activity Relationships(QSAR) models showed accuracy of 67.28%, 78.00% and 75.46%, for the isoforms SULT1A1, SULT1A3 and SULT1E1, respectively.
Overexpression of EST (显示 MAP3K8 抗体) promoted adipogenesis.
Report diterpenoid extracts from Leonurus sibiricus L. with estrogen sulfotransferase inhibitory activity.
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
, estrone sulfotransferase
, ste2 gene for estrogen sulfotransferase
, sulfotransferase, estrogen-preferring
, estrogen sulfotransferase
, sulfotransferase 1E1
, estrogen sulfotransferase, testis isoform
, sulfotransferase, estrogen preferring
, adrenocortical estrogen sulfotransferase
, sulfotransferase family 1E, estrogen-preferring, member 1
, sulfotransferase family 1E member 1 L homeolog
, sulfotransferase family 1E member 1 S homeolog