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SMC1A 抗体

(Structural Maintenance of Chromosomes 1A (SMC1A))
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008].
SMC1A 抗体  (pSer957) SMC1A 抗体  (pSer957) SMC1A 抗体 (pSer957) (ABIN3019554)

SMC1A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

SMC1A 抗体 SMC1A 抗体 SMC1A 抗体 (ABIN7270614)

SMC1A 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

SMC1A 抗体 SMC1A 抗体 SMC1A 抗体 (ABIN969406)

SMC1A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B6 unconjugated

SMC1A 抗体 by 适用

Find SMC1A 抗体 for a variety of species such as anti-Human SMC1A, anti-Mouse SMC1A, anti-Rat SMC1A. The species listed below are among those available. Click on a link to go to the corresponding products.

SMC1A 抗体 by 应用范围

Find SMC1A 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find SMC1A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SMC1A 抗体 by 抗原表位

Find SMC1A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SMC1A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SMC1A 抗体. Click on a link to go to the corresponding products.

SMC1A 抗体 by 克隆

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SMC1A 抗体 by 标记

Find SMC1A 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SMC1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (7)
Cat. No. ABIN3019554
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN7270614
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN969406
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7270613
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7265084
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7127813
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7251964
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN563572
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP, ChIP-seq
Validations
  • (3)
Cat. No. ABIN6972754
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IP
Validations
  • (3)
Cat. No. ABIN2856699
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN2780766
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN700930
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN745868
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7170857
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SMC1A 抗体

Wang, Jette, Moussienko, Bebb, Lees-Miller: "ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib." in: Translational oncology, Vol. 10, Issue 2, pp. 190-196, (2017) (PubMed).

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, (2015) (PubMed).

Valdez, Li, Murray, Ji, Liu, Popat, Champlin, Andersson: "Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators." in: Experimental hematology, Vol. 43, Issue 6, pp. 448-61.e2, (2015) (PubMed).

Houlihan, Feng: "The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation." in: eLife, Vol. 3, pp. e03297, (2014) (PubMed).

Lee, Martin, Nakamura, Azghadi, Amiri, Ben-David, Perlman, Gatti, Hu, Lowry: "SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs." in: Nature communications, Vol. 4, pp. 1824, (2013) (PubMed).

Puccini, Shalini, Voss, Gatei, Wilson, Hiwase, Lavin, Dorstyn, Kumar: "Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19920-5, (2013) (PubMed).

Williamson, Kubota, Hamill, Klimowicz, Ye, Muzik, Dean, Tu, Gilley, Magliocco, McKay, Bebb, Lees-Miller: "Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53." in: EMBO molecular medicine, Vol. 4, Issue 6, pp. 515-27, (2012) (PubMed).

Valdez, Nieto, Murray, Li, Wang, Champlin, Andersson: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." in: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).

Daniel, Pellegrini, Lee, Guo, Filsuf, Belkina, You, Paull, Sleckman, Feigenbaum, Nussenzweig: "Loss of ATM kinase activity leads to embryonic lethality in mice." in: The Journal of cell biology, Vol. 198, Issue 3, pp. 295-304, (2012) (PubMed).

Valdez, Murray, Nieto, Li, Wang, Champlin, Andersson: "Synergistic cytotoxicity of the DNA alkylating agent busulfan, nucleoside analogs and suberoylanilide hydroxamic acid in lymphoma cell lines." in: Leukemia & lymphoma, Vol. 53, Issue 5, pp. 973-81, (2012) (PubMed).

Aliases for SMC1A 抗体

structural maintenance of chromosomes 1A (SMC1A) 抗体
structural maintenance of chromosomes 1A (smc1a) 抗体
structural maintenance of chromosomes 1A (Smc1a) 抗体
structural maintenance of chromosomes 1A b (smc1ab) 抗体
structural maintenance of chromosomes 1A L homeolog (smc1a.L) 抗体
5830426I24Rik 抗体
CDLS2 抗体
DXS423E 抗体
mKIAA0178 抗体
NV15570 抗体
SB1.8 抗体
Sb1.8 抗体
SMC-1A 抗体
SMC1 抗体
Smc1 抗体
smc1 抗体
smc1a 抗体
smc1aa 抗体
SMC1alpha 抗体
Smc1alpha 抗体
SMC1L1 抗体
Smc1l1 抗体
smc1l1 抗体
SMCB 抗体
Smcb 抗体
xSMC1 抗体
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