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抗Human NKAP 抗体:
抗Mouse (Murine) NKAP 抗体:
抗Rat (Rattus) NKAP 抗体:
SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores
NKAP is required for T cell maturation and the acquisition of functional competency
NKAP is a novel nuclear regulator of TNF- and IL-1-induced NF-kappaB activation
NKAP functions as a transcriptional repressor, acting on Notch target genes, and is required for alphabeta T cell development.
This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
, NF-kappaB activating protein
, NFKB activating protein-like
, chromosome 6 open reading frame 194-like
, nuclear NF-kappaB activating protein
, uncharacterized protein LOC779418
, NFKB activating protein like