Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 产品
(Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
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This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008].
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Featured Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Categories
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 抗体
High quality antibodies with extensive validation data.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN520465
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Pig, Rabbit
Application
WB, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN2781788
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN562991
Quantity
50 μL
Datasheet
Datasheet
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959725
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962626
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959723
Quantity
96 tests
Datasheet
Datasheet
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321302
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3097340
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3128113
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Products
: "TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model." in: Neuropharmacology, Vol. 111, pp. 142-159, (2016) (PubMed).: "The role of 5α-reductase type 1 associated with intratumoral dihydrotestosterone concentrations in human endometrial carcinoma." in: Molecular and cellular endocrinology, Vol. 401, pp. 56-64, (2015) (PubMed).
: "Hamster SRD5A3 lacks steroid 5α-reductase activity in vitro." in: Steroids, Vol. 94, pp. 41-50, (2015) (PubMed).
: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
: "Resistance training restores muscle sex steroid hormone steroidogenesis in older men." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 4, pp. 1891-7, (2014) (PubMed).
: "Seoritae extract reduces prostate weight and suppresses prostate cell proliferation in a rat model of benign prostate hyperplasia." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 475876, (2014) (PubMed).
: "46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5α-reductase type-2 (SRD5A2) gene." in: Molecular genetics & genomic medicine, Vol. 2, Issue 4, pp. 292-6, (2014) (PubMed).
: "DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats." in: Calcified tissue international, Vol. 89, Issue 2, pp. 105-10, (2011) (PubMed).
: "Molecular analysis of the SRD5A2 in 46,XY subjects with incomplete virilization: the P212R substitution of the steroid 5alpha-reductase 2 may constitute an ancestral founder mutation in Mexican ..." in: Journal of andrology, Vol. 31, Issue 4, pp. 358-64, (2010) (PubMed).
: "VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 10, pp. 3223-9, (2008) (PubMed).
Synonyms and alternative names related to Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
steroid 5 alpha-reductase 2 (SRD5A2), steroid 5 alpha-reductase 2 (Srd5a2), steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2), 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (LOC100125532), steroid-5-alpha-reductase, alpha polypeptide 2a (srd5a2a), steroid-5-alpha-reductase, alpha polypeptide 2b (srd5a2b), 5ART2, CH73-233A22.6, S5AR 2, SRD5A2, Srd5a2, SRD5alpha2, wu:fk70d02, zgc:109942, zgc:112208, zgc:112455Protein level used designations for Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 5 alpha-SR2
- S5AR 2
- SR type 2
- steroid 5-alpha-reductase 2
- type II 5-alpha reductase
- steroid 5 alpha reductase type2
- prostatic steroid 5-alpha-reductase type II
- steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- steroid-5-alpha-reductase alpha polypeptide 2
- steroid-5-alpha-reductase, alpha polypeptide 2b
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