KCNQ4 抗体
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
KCNQ4 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N43-6 (Formerly S43-6) unconjugated
recommended
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KCNQ4 抗体 by 适用
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Popular KCNQ4 抗体
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Application
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Cat. No.
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Datasheet
Reactivity
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Application
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- (1)
Cat. No.
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Quantity
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Application
WB, IHC, IP, IF, ICC, AA
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Cat. No.
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Quantity
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Application
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Quantity
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Datasheet
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Application
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Quantity
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ABIN2483173
Quantity
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Cat. No.
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Quantity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, IHC, ISt
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
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Latest Publications for our KCNQ4 抗体
: "Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss." in: Frontiers in aging neuroscience, Vol. 12, pp. 83, (2020) (PubMed).: "Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea." in: The Journal of physiology, Vol. 598, Issue 1, pp. 151-170, (2020) (PubMed).
: "GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing." in: Frontiers in neural circuits, Vol. 12, pp. 65, (2019) (PubMed).
: "Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection." in: Cardiovascular research, Vol. 110, Issue 1, pp. 40-50, (2016) (PubMed).
: "Role of Kv7 channels in responses of the pulmonary circulation to hypoxia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 308, Issue 1, pp. L48-57, (2015) (PubMed).
: "K(V)7.4 channels participate in the control of rodent renal vascular resting tone." in: Acta physiologica (Oxford, England), Vol. 214, Issue 3, pp. 402-14, (2015) (PubMed).
: "Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats." in: Basic & clinical pharmacology & toxicology, Vol. 110, Issue 2, pp. 145-53, (2014) (PubMed).
: "KCNQ and KCNE potassium channel subunit expression in bovine retinal pigment epithelium." in: Experimental eye research, Vol. 116, pp. 424-32, (2014) (PubMed).
: "The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. E2472-81, (2014) (PubMed).
: "Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 274-84, (2013) (PubMed).
Aliases for KCNQ4 抗体
potassium voltage-gated channel subfamily Q member 4 (KCNQ4) 抗体potassium channel, voltage gated KQT-like subfamily Q, member 4 (kcnq4) 抗体
potassium voltage-gated channel subfamily Q member 4 (Kcnq4) 抗体
potassium voltage-gated channel, subfamily Q, member 4 (Kcnq4) 抗体
DFNA2 抗体
DFNA2A 抗体
k(v)7.4 抗体
KCNQ4 抗体
kv7.4 抗体
KV7.4 抗体
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