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FBXO11 抗体

(F-Box Protein 11 (FBXO11))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
FBXO11 抗体  (AA 744-843) FBXO11 抗体  (AA 744-843) FBXO11 抗体 (AA 744-843) (ABIN566432)

FBXO11 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated

FBXO11 抗体  (AA 65-160) FBXO11 抗体  (AA 65-160) FBXO11 抗体 (AA 65-160) (ABIN1386847)

FBXO11 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

FBXO11 抗体  (AA 1-843) FBXO11 抗体  (AA 1-843) FBXO11 抗体 (AA 1-843) (ABIN529215)

FBXO11 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

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Popular FBXO11 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN566432
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN1386847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN529215
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7261998
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN626116
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, ChIP
Validations
  • (3)
Cat. No. ABIN2774788
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC
Validations
  • (3)
Cat. No. ABIN559708
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7166759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6391388
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6743169
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6748261
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6146236
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6140512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1399291
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1399287
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our FBXO11 抗体

Clijsters, Hoencamp, Calis, Marzio, Handgraaf, Cuitino, Rosenberg, Leone, Pagano: "Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs." in: Molecular cell, Vol. 74, Issue 6, pp. 1264-1277.e7, (2019) (PubMed).

Pagan, Marzio, Jones, Saraf, Jallepalli, Florens, Washburn, Pagano: "Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing." in: Nature cell biology, Vol. 17, Issue 1, pp. 31-43, (2014) (PubMed).

Horn, Geisen, Cermak, Becker, Nakamura, Klein, Pagano, Antebi: "DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation." in: Developmental cell, Vol. 28, Issue 6, pp. 697-710, (2014) (PubMed).

Rossi, Duan, Jeong, Horn, Saraf, Florens, Washburn, Antebi, Pagano: "Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase." in: Molecular cell, Vol. 49, Issue 6, pp. 1159-66, (2013) (PubMed).

Duan, Cermak, Pagan, Rossi, Martinengo, di Celle, Chapuy, Shipp, Chiarle, Pagano: "FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas." in: Nature, Vol. 481, Issue 7379, pp. 90-3, (2012) (PubMed).

Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, (2008) (PubMed).

Aliases for FBXO11 抗体

F-box protein 11 (FBXO11) 抗体
F-box protein 11 (Fbxo11) 抗体
F-box protein 11 L homeolog (fbxo11.L) 抗体
F-box protein 11a (fbxo11a) 抗体
F-box only protein 11 (CpipJ_CPIJ009919) 抗体
F-box only protein 11 (CpipJ_CPIJ017549) 抗体
F-box only protein 11 (Bm1_52225) 抗体
hypothetical protein (LOAG_16571) 抗体
F-box protein 11 (fbxo11) 抗体
F-box protein 11 (LOC100115478) 抗体
C80048 抗体
DKFZp459P2410 抗体
FBX11 抗体
fbxo11 抗体
FBXO11 抗体
Fbxo11 抗体
im:6906507 抗体
Jf 抗体
MGC84634 抗体
PRMT9 抗体
UBR6 抗体
VIT1 抗体
Vit1 抗体
wu:fj83f06 抗体
zgc:153171 抗体
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