Use your antibodies-online credentials, if available.
抗Human CHRNA9 抗体:
抗Rat (Rattus) CHRNA9 抗体:
抗Mouse (Murine) CHRNA9 抗体:
Human Polyclonal CHRNA9 Primary Antibody for WB - ABIN1944733
Sgard, Charpantier, Bertrand, Walker, Caput, Graham, Bertrand, Besnard: A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit. in Molecular pharmacology 2001
Show all 5 Pubmed References
Cow (Bovine) Polyclonal CHRNA9 Primary Antibody for WB - ABIN2792251
Peng, Ferris, Matthews, Hiel, Lopez-Albaitero, Lustig: Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes. in Life sciences 2004
Show all 2 Pubmed References
phosphocholine inhibits ion-channel function of ATP receptor P2X7 in monocytic cells via nAChR containing alpha9 and alpha10 subunits.
Behavioural and physiological stress-induced changes observed in alpha9-nAChR KO mice demonstrate a novel role of the alpha9alpha10-nAChR in mounting a normal stress response. The lack of functioning alpha9alpha10-nAChRs leads to negative affective changes after a relatively short period of stress. KO mice exhibited unusual patterns of circadian activity and a dysfunction in reward seeking after a period of reduced acc...
Chemotherapy induced cold allodynia is reduced in alpha 9 knockout mice.
The rare variants in CHRNA9 were significantly associated with smoking status.
Our findings support a significant interaction effect existing between the CHRNA9 gene and smoking exposure on the risk of breast cancer development.
CHRNA9 polymorphisms are associated with non-small cell lung cancer.
Thia case-control analysis revealed that an increased risk of lung cancer is associated with two SNPs in CHRNA9, rs56159866 and rs6819385.
Data suggest that the biologic activities of Alpha9 nicotinic receptor (CHRNA9) may be regulated at the splicing level, and genetic polymorphisms in CHRNA9 affecting protein levels, amino acid sequence and RNA splicing may influence the risk for lung cancer.
A two order of magnitude species difference in potency of alpha-conotoxin RgIA is reported for rat versus human alpha9alpha10 nAChR.
Estrogen receptor-alpha plays a central role in mediating alpha9-nAChR gene up-regulation in response to either nicotine or estradiol stimulation.
Significant increases in the alpha9-nAChR mRNA and protein levels in MCF-7 cells were detected 6 h after nicotine treatment. Nicotine- and estrogen-induced alpha9-nicotinic acetylcholine receptor upregulation was blocked by (-)-epigallocatechin-3-gallate.
These results suggest that alpha9-nAChR-mediated cyclin D3 overexpression is important for nicotine-induced transformation of normal human breast epithelial cells.
The alpha9-nAChR is important for nicotine-induced transformation of normal human breast epithelial cells. Results imply that receptor-mediated carcinogenic signals play a decisive role in biological functions related to human breast cancer development.
Chromosome location and characterization of the CHRNA9 gene.
two cis-elements of the alpha9 nicotinic receptor subunit promoter control in opposite ways the basal transcriptional activity of the gene
Signaling through alpha9 AChR is critical for completion of the very early stages of epithelialization.
This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.
, cholinergic receptor, nicotinic, alpha polypeptide 9
, neuronal acetylcholine receptor subunit alpha-9
, nicotinic acetylcholine receptor subunit alpha-9
, NACHR alpha 9
, acetylcholine receptor, neuronal nicotinic, alpha-9 subunit
, neuronal acetylcholine receptor protein, alpha-9 subunit
, nicotinic acetylcholine receptor subunit alpha 9
, acetylcholine receptor alpha 9 subunit (nAChR)
, cholinergic receptor, nicotinic, alpha 9