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FGFR1 蛋白

(Fibroblast Growth Factor Receptor 1 (FGFR1))
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
FGFR1 Protein (AA 22-374) (His-Avi Tag) FGFR1 Protein (AA 22-374) (His-Avi Tag) FGFR1 Protein (AA 22-374) (His-Avi Tag) (ABIN7274633)

FGFR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

FGFR1 Protein (AA 400-820) (His-GST) FGFR1 Protein (AA 400-820) (His-GST) FGFR1 Protein (AA 400-820) (His-GST) (ABIN5570013)

FGFR1 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active

FGFR1 Protein (AA 624-822) (His-IF2DI Tag) FGFR1 Protein (AA 624-822) (His-IF2DI Tag) FGFR1 Protein (AA 624-822) (His-IF2DI Tag) (ABIN7122955)

FGFR1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

FGFR1 蛋白 by Grade

Find FGFR1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

FGFR1 蛋白 by Origin

Find FGFR1 蛋白 for a variety of species such as anti-Human FGFR1, anti-Mouse FGFR1, anti-Rat FGFR1. The species listed below are among those available. Click on a link to go to the corresponding products.

FGFR1 蛋白 by Source

Here you will find FGFR1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FGFR1 蛋白 by 蛋白类型

Here you can find FGFR1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

FGFR1 蛋白 by 应用范围

Find FGFR1 蛋白 validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

FGFR1 蛋白 by 生物活性

Find FGFR1 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular FGFR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274633
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5570013
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122955
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354031
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354029
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354028
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317102
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320381
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320382
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN5570034
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3112764
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092599
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092598
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133088
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133086
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FGFR1 蛋白

Lohr, Mock, Beckhove, Herold-Mende: "Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature." in: Anticancer research, Vol. 35, Issue 5, pp. 2681-90, (2015) (PubMed).

Kim, Al-Hilal, Chung, Kim, Ryu, Son, Byun: "Antiangiogenic and anticancer effect of an orally active low molecular weight heparin conjugates and its application to lung cancer chemoprevention." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 199, pp. 122-31, (2015) (PubMed).

Teodorczyk, Kleber, Wollny, Sefrin, Aykut, Mateos, Herhaus, Sancho-Martinez, Hill, Gieffers, Sykora, Weichert, Eisen, Trumpp, Sprick, Bergmann, Welsch, Martin-Villalba: "CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma." in: Cell death and differentiation, Vol. 22, Issue 7, pp. 1192-202, (2015) (PubMed).

Tsimafeyeu, Zaveleva, Stepanova, Low: "OM-RCA-01, a novel humanized monoclonal antibody targeting fibroblast growth factor receptor 1, in renal cell carcinoma model." in: Investigational new drugs, Vol. 31, Issue 6, pp. 1436-43, (2013) (PubMed).

Aliases for FGFR1 蛋白

fibroblast growth factor receptor (FGFR) 蛋白
fibroblast growth factor receptor (fgfr) 蛋白
fibroblast growth factor receptor 1 S homeolog (fgfr1.S) 蛋白
basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849) 蛋白
heartless (htl) 蛋白
fibroblast growth factor receptor 1 (fgfr1) 蛋白
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L) 蛋白
fibroblast growth factor receptor 1 (FGFR1) 蛋白
fibroblast growth factor receptor 1 (Fgfr1) 蛋白
Fibroblast growth factor receptor 1 (Fgfr1) 蛋白
fibroblast growth factor receptor 1 L homeolog (fgfr1.L) 蛋白
fibroblast growth factor receptor 1a (fgfr1a) 蛋白
ach 蛋白
AW208770 蛋白
bFGF-R-1 蛋白
bfgfr 蛋白
BFGFR 蛋白
cb231 蛋白
cd331 蛋白
CD331 蛋白
cd333 蛋白
cek 蛋白
CEK 蛋白
cek2 蛋白
CG7223 蛋白
CT22273 蛋白
CT39172 蛋白
DFGF-R1 蛋白
DFGF-R2 蛋白
DFR-1 蛋白
Dfr-1 蛋白
DFR1 蛋白
Dfr1 蛋白
DFR1/DFGF-R2 蛋白
Dmel\\CG7223 蛋白
DmHD-38 蛋白
DPR3 蛋白
Dtk1 蛋白
dtk1 蛋白
DTRK(FR1) 蛋白
Eask 蛋白
EMS2 蛋白
FGF-R2 蛋白
fgfbr 蛋白
FGFBR 蛋白
FGFR 蛋白
fgfr 蛋白
fgfr-1 蛋白
FGFR-1 蛋白
Fgfr-1 蛋白
fgfr-3 蛋白
fgfr1 蛋白
FGFR2 蛋白
FGFRI 蛋白
flg 蛋白
FLG 蛋白
FLG-1 蛋白
flt-2 蛋白
FLT-2 蛋白
Flt-2 蛋白
flt2 蛋白
FLT2 蛋白
FR1 蛋白
Fr1 蛋白
hbgfr 蛋白
HBGFR 蛋白
HD-38 蛋白
HH2 蛋白
hsfgfr3ex 蛋白
Hspy 蛋白
Htl 蛋白
HTL/FGFR1 蛋白
i79 蛋白
i100 蛋白
i150 蛋白
j372 蛋白
jtk4 蛋白
kal2 蛋白
KAL2 蛋白
n-sam 蛋白
N-SAM 蛋白
ogd 蛋白
OGD 蛋白
sb:cb231 蛋白
Tk1 蛋白
X1FGFR 蛋白
x1fgfr 蛋白
XFGFR-1 蛋白
xfgfr1 蛋白
XFGFRA2 蛋白
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