anti-小鼠 TRKA 抗体 for Immunofluorescence

Recommended TRKA Antibody (supplied by: Log in to see )

抗原
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) 抗体
  • MTC
  • TRK
  • TRK1
  • TRKA
  • Trk-A
  • p140-TrkA
  • Trk
  • C80751
  • Tkr
  • TrkA
  • trk
  • trka
  • CTRKA
  • trkA
  • neurotrophic receptor tyrosine kinase 1
  • neurotrophic tyrosine kinase, receptor, type 1
  • NTRK1
  • Ntrk1
  • ntrk1
适用
人, 小鼠
426
261
208
2
2
宿主

397
54
4
3
2
克隆类型
多克隆
标记
This TRKA antibody is un-conjugated
17
16
16
11
9
8
8
8
8
7
7
7
7
7
7
7
6
2
2
1
1
1
1
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
274
166
123
88
59
52
50
40
19
12
9
5
4
1
1
1
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产品编号 ABIN3031990
$ 411.13
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.754771 ABIN3183034 ELISA IF Rabbit IgG pTyr496 Log in to see Polyclonal 0
10 ABIN5531716 FACS IF WB Rabbit Ig Fraction Log in to see Polyclonal 0
8.308159 ABIN1531406 IF ELISA Rabbit IgG AA 471-520, pTyr496 Log in to see Polyclonal 0
7 ABIN652382 FACS IF WB Rabbit Ig Fraction Log in to see Polyclonal 0
1 ABIN2755760 IC IF IHC WB Rabbit pTyr496 Log in to see Polyclonal 0
1 ABIN2884444 ELISA IF Rabbit IgG pTyr496 Log in to see Polyclonal 0
1 ABIN1808770 FACS IF WB Rabbit Log in to see Polyclonal 0
1 ABIN1003520 IF IP WB Rabbit phosphospecific Log in to see Polyclonal 0

General

抗原 Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) 抗体
适用 人, 小鼠
(426), (261), (208), (2), (2)
宿主
(397), (54), (4), (3), (2)
克隆类型
多克隆
标记 This TRKA antibody is un-conjugated
(17), (16), (16), (11), (9), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (6), (2), (2), (1), (1), (1), (1)
应用范围 Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(274), (166), (123), (88), (59), (52), (50), (40), (19), (12), (9), (5), (4), (1), (1), (1)
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TRKA抗体详情

TRKA目标详情 使用细节 贮存及处理 图像
纯化方法 Purified
免疫原 This TrkA antibody was produced from rabbits immunized with TrkA his fusion protein
亚型 Ig Fraction
Plasmids, Primers & others

TRKA目标详情

TRKA抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 TrkA (NTRK1 Antibody 摘要)
背景 TrkA is a receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. [UniProt]
UniProt P04629
途径 RTK signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process

使用细节

TRKA抗体详情 TRKA目标详情 贮存及处理 图像 回页首
应用备注 Titration of the TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
限制 仅限研究用

贮存及处理

TRKA抗体详情 TRKA目标详情 使用细节 图像 回页首
状态 Liquid
缓冲液 In 1X PBS,  pH 7.4, with 0.09 % sodium azide
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Aliquot the TrkA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

图像

TRKA抗体详情 TRKA目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Immunofluorescence (IF) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody (ABIN3031990) Confocal immunofluorescent analysis of TrkA antibody with MDA-MB231 cells followed by...
Flow Cytometry (FACS) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody (ABIN3031990) TrkA antibody flow cytometric analysis of WiDr cells (green) compared to a negative c...
Western Blotting (WB) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody (ABIN3031990) Western blot analysis of TrkA antibody and mouse brain tissue lysate. Observed molecu...