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SHC1 抗体

(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
SHC1 抗体  (AA 171-280) SHC1 抗体  (AA 171-280) SHC1 抗体 (AA 171-280) (ABIN562866)

SHC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3F4 unconjugated

SHC1 抗体  (AA 385-495) SHC1 抗体  (AA 385-495) SHC1 抗体 (AA 385-495) (ABIN5542463)

SHC1 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F7C7 unconjugated

SHC1 抗体  (C-Term) SHC1 抗体  (C-Term) SHC1 抗体 (C-Term) (ABIN3044111)

SHC1 适用: 人, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

SHC1 抗体 by 适用

Find SHC1 抗体 for a variety of species such as anti-Human SHC1, anti-Mouse SHC1, anti-Rat SHC1. The species listed below are among those available. Click on a link to go to the corresponding products.

SHC1 抗体 by 应用范围

Find SHC1 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SHC1 抗体 by 抗体来源

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SHC1 抗体 by 抗原表位

Find SHC1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SHC1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SHC1 抗体. Click on a link to go to the corresponding products.

SHC1 抗体 by 克隆

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SHC1 抗体 by 标记

Find SHC1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SHC1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), PLA
Validations
  • (8)
Cat. No. ABIN562866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, FACS
Validations
  • (6)
Cat. No. ABIN5542463
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC, IHC (fro)
Validations
  • (8)
Cat. No. ABIN3044111
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN3043923
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC, IHC (fro)
Validations
  • (11)
Cat. No. ABIN3032555
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7435826
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7263733
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255897
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, IHC (p), PLA
Validations
  • (4)
Cat. No. ABIN574341
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN745913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7139005
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN700990
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (2)
Cat. No. ABIN745973
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7169511
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SHC1 抗体

Wang, Zhang, Diao, Zhang: "Protective Effects of Curcumin against Sodium Arsenite-induced Ovarian Oxidative Injury in a Mouse Model." in: Chinese medical journal, Vol. 130, Issue 9, pp. 1026-1032, (2018) (PubMed).

Bhat, Baba, Adams, Khanday: "Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells." in: British journal of cancer, Vol. 110, Issue 3, pp. 706-14, (2014) (PubMed).

Trnka, Burlingame et al.: "Topographic studies of the GroEL-GroES chaperonin complex by chemical cross-linking using diformyl ethynylbenzene: the power of high resolution electron transfer dissociation for determination of..." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 10, pp. 2306-17, (2010) (PubMed).

Ursini-Siegel, Cory, Zuo, Hardy, Rexhepaj, Lam, Schade, Jirstrom, Bjur, Piccirillo, Denardo, Coussens, Brennan, Gallagher, Park, Pawson, Hallett, Muller: "Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response." in: Cancer research, Vol. 70, Issue 20, pp. 7776-87, (2010) (PubMed).

Ranieri, Fusco, Panieri, Labate, Mele, Tesori, Ferrara, Maulucci, De Spirito, Martorana, Galeotti, Pani: "Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 30, pp. 13420-5, (2010) (PubMed).

Ginés, Paoletti, Alberch: "Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21537-48, (2010) (PubMed).

Ma, Liu, Wu, Terada: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, (2010) (PubMed).

Goshima, Kawamura, Fukumoto, Miura, Honma, Satoh, Wakamatsu, Yamamoto, Kimura, Nishikawa, Andoh, Iida, Ishikawa, Ito, Kagawa, Kaminaga, Kanehori, Kawakami, Kenmochi, Kimura, Kobayashi, Kuroita et al.: "Human protein factory for converting the transcriptome into an in vitro-expressed proteome,. ..." in: Nature methods, Vol. 5, Issue 12, pp. 1011-7, (2008) (PubMed).

Hardy, Li, Wang, Sedy, Fawcett, Frank, Kucera, Pawson: "Combinatorial ShcA docking interactions support diversity in tissue morphogenesis." in: Science (New York, N.Y.), Vol. 317, Issue 5835, pp. 251-6, (2007) (PubMed).

Zhang, Lorenz, Ravichandran: "Role of Shc in T-cell development and function." in: Immunological reviews, Vol. 191, pp. 183-95, (2003) (PubMed).

Aliases for SHC1 抗体

SHC adaptor protein 1 (SHC1) 抗体
Shc1p (SHC1) 抗体
squalene--hopene cyclase (shc1) 抗体
SHC adaptor protein 1 (Shc1) 抗体
SHC (Src homology 2 domain containing) transforming protein 1 (shc1) 抗体
SHC (Src homology 2 domain containing) transforming protein 1 L homeolog (shc1.L) 抗体
src homology 2 domain-containing transforming protein C1 (Shc1) 抗体
p66 抗体
P66shc 抗体
p66shc 抗体
SHC 抗体
shc 抗体
Shc 抗体
SHC1 抗体
SHCA 抗体
ShcA 抗体
si:dkey-246i14.4 抗体
wu:fc10h03 抗体
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