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|抗原||PTK7 Protein tyrosine Kinase 7 (PTK7) 抗体|
|适用||人, 小鼠, 大鼠 其他选择|
|标记||This PTK7 antibody is un-conjugated 其他选择|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
PTK7抗体详情PTK7目标详情 使用细节 贮存及处理 图像
|特异性||This antibody detects PTK7 at C-term.|
|交叉反应 （详细）||Species reactivity (tested):Human, mouse, rat|
|纯化方法||Peptide affinity chromatography|
|免疫原||PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.|
PTK7目标详情PTK7抗体详情 使用细节 贮存及处理 图像 回页首
|别名||PTK7 / CCK4 (PTK7 Antibody 摘要)|
|背景||Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7|
|途径||RTK signaling, Tube Formation|
使用细节PTK7抗体详情 PTK7目标详情 贮存及处理 图像 回页首
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
贮存及处理PTK7抗体详情 PTK7目标详情 使用细节 图像 回页首
|缓冲液||PBS containing 0.02 % sodium azide|
|注意事项||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|注意事项||Avoid repeated freezing and thawing.|
|储存条件||4 °C/-20 °C|
|储存方法||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.|