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PAK4 抗体

(P21-Activated Kinase 4 (PAK4))
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PAK4 抗体  (AA 299-542) PAK4 抗体  (AA 299-542) PAK4 抗体 (AA 299-542) (ABIN7439984)

PAK4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PAK4 抗体  (AA 1-426) PAK4 抗体  (AA 1-426) PAK4 抗体 (AA 1-426) (ABIN7169132)

PAK4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PAK4 抗体  (AA 187-216) PAK4 抗体  (AA 187-216) PAK4 抗体 (AA 187-216) (ABIN3032118)

PAK4 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

PAK4 抗体 by 适用

Find PAK4 抗体 for a variety of species such as anti-Human PAK4, anti-Mouse PAK4, anti-Rat PAK4. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PAK4 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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PAK4 抗体 by 抗原表位

Find PAK4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PAK4 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PAK4 抗体. Click on a link to go to the corresponding products.

PAK4 抗体 by 克隆

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PAK4 抗体 by 标记

Find PAK4 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PAK4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7439984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7169132
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN3032118
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Rat
Application WB, ELISA, IP
Validations
  • (1)
  • (1)
Cat. No. ABIN540950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, FACS, IHC (p)
Validations
  • (2)
Cat. No. ABIN1921165
Quantity 200 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Rat
Application WB, ELISA, IP
Validations
  • (1)
  • (1)
Cat. No. ABIN541035
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN6746289
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6145188
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3032119
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (3)
Cat. No. ABIN5534399
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN564474
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, IF, ICC
Validations
  • (1)
Cat. No. ABIN2626537
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN5585195
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392437
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7297752
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PAK4 抗体

He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

Cianciola, Chung, Manor, Carlin: "Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum." in: Journal of virology, Vol. 91, Issue 6, (2017) (PubMed).

Liu, Yang, Liu, Liu, Zhang, Xu, Zhu, Xu: "p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma." in: Urologic oncology, Vol. 33, Issue 5, pp. 205.e13-21, (2015) (PubMed).

Cotteret, Jaffer, Beeser, Chernoff: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, (2003) (PubMed).

Lu, Pan, Devaux, Ray: "p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10374-80, (2003) (PubMed).

Jaffer, Chernoff: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).

Callow, Clairvoyant, Zhu, Schryver, Whyte, Bischoff, Jallal, Smeal: "Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 550-8, (2002) (PubMed).

Abo, Qu, Cammarano, Dan, Fritsch, Baud, Belisle, Minden: "PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia." in: The EMBO journal, Vol. 17, Issue 22, pp. 6527-40, (1999) (PubMed).

Marte, Downward: "PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond." in: Trends in biochemical sciences, Vol. 22, Issue 9, pp. 355-8, (1997) (PubMed).

Knaus, Morris, Dong, Chernoff, Bokoch: "Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors." in: Science (New York, N.Y.), Vol. 269, Issue 5221, pp. 221-3, (1995) (PubMed).

Aliases for PAK4 抗体

p21 (RAC1) activated kinase 4 (PAK4) 抗体
p21 protein (Cdc42/Rac)-activated kinase 4 (Pak4) 抗体
p21 (RAC1) activated kinase 4 (Pak4) 抗体
p21 protein (Cdc42/Rac)-activated kinase 4 (pak4) 抗体
5730488L07Rik 抗体
AW555722 抗体
im:5916170 抗体
mKIAA1142 抗体
wu:fd12b01 抗体
zgc:92014 抗体
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