anti-小鼠 MET 抗体 for Immunohistochemistry (Paraffin-embedded Sections)
Recommended MET Antibody (supplied by: Log in to see )
- 抗原
-
Met Proto-Oncogene (MET) 抗体
show Synonyms for this Antigen- AUTS9
- HGFR
- RCCP2
- c-Met
- AI838057
- HGF
- Par4
- Hgfr
- c-met
- MET proto-oncogene, receptor tyrosine kinase
- met proto-oncogene
- MET
- Met
- 抗原表位
-
AA 25-75
其他选择 - 适用
-
人, 小鼠, 大鼠
其他选择 - 宿主
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兔
其他选择 - 克隆类型
- 标记
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This MET antibody is un-conjugated
其他选择 - 应用范围
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Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
其他选择 - 选项
- Supplier
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- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 12.4843445 | ABIN387741 | IF IHC (p) WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 4AT44 | 0 | ||
| 12.4843445 | ABIN5611613 | EIA IHC (p) WB | Rabbit | IgG | C-Term | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN387742 | IF IHC (p) WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 6AT203 | 0 | ||
| 1 | ABIN387743 | IF IHC (p) WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 6AT1785 | 0 | ||
| 1 | ABIN958012 | IHC (p) WB | Rabbit | IgG | pTyr1349 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN733658 | IF (p) IHC (p) WB | Rabbit | IgG | AA 1345-1385, pTyr1365 | Log in to see | Polyclonal | 1 | ||
| 1 | ABIN743843 | IF (p) IHC (p) WB | Rabbit | IgG | pTyr1234, pTyr1235, AA 1220-1240 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN401652 | IHC (p) WB | Rabbit | AA 1001-1005 | Log in to see | Polyclonal | 2 | |||
| 1 | ABIN2851988 | IHC (p) ELISA WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 4AT44 | 0 | ||
| 1 | ABIN1804073 | IF IHC (p) WB | Mouse | IgG1 | Log in to see | 4AT44 | 0 | |||
| 1 | ABIN2177593 | IF (p) IHC (p) WB | Rabbit | IgG | pTyr1003 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN743852 | IHC (p) WB | HRP | Rabbit | IgG | pTyr1234, pTyr1235, AA 1220-1240 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN407142 | FACS IHC (p) IP IHC ELISA WB | Mouse | IgG1 | Log in to see | 6AT44 | 1 | |||
| 1 | ABIN5550863 | EIA IHC (p) WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 4AT44 | 0 | ||
| 1 | ABIN671670 | IHC (p) WB | HRP | Rabbit | IgG | AA 25-75 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN733667 | IHC (p) WB | HRP | Rabbit | IgG | AA 1345-1385, pTyr1365 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN743845 | IHC (p) WB | Biotin | Rabbit | IgG | pTyr1234, pTyr1235, AA 1220-1240 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN5550864 | EIA IHC (p) WB | Mouse | IgG1 | Catalytic Domain | Log in to see | 6AT203 | 0 | ||
| 1 | ABIN671663 | IHC (p) WB | Biotin | Rabbit | IgG | AA 25-75 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN733660 | IHC (p) WB | Biotin | Rabbit | IgG | AA 1345-1385, pTyr1365 | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| 抗原 | Met Proto-Oncogene (MET) 抗体 |
| 抗原表位 | AA 25-75 其他选择 |
| 适用 | 人, 小鼠, 大鼠 其他选择 |
| 宿主 | 兔 其他选择 |
| 克隆类型 | |
| 标记 | This MET antibody is un-conjugated 其他选择 |
| 应用范围 |
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
其他选择
|
|
4个引用可参考 |
| Supplier | Log in to see |
MET抗体详情MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN671661) 图像 |
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| 纯化方法 | Purified by Protein A. |
| 免疫原 | KLH conjugated synthetic peptide derived from human Met (c-Met) |
| 亚型 | IgG |
MET目标详情MET抗体详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN671661) 图像 回页首 |
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| 抗原 | |
| 别名 | Met (MET Antibody 摘要) |
| 背景 |
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells. Subcellular location: Extracellular Synonyms: HGFR, AUTS9, RCCP2, c-Met, Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET |
| 基因ID | 4233 |
| UniProt | P08581 |
| 途径 | RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor |
使用细节MET抗体详情 MET目标详情 贮存及处理 References for anti-MET antibody (ABIN671661) 图像 回页首 |
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| 应用备注 |
WB 1:100-1000 FCM 1:20-100 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
| 限制 | 仅限研究用 |
贮存及处理MET抗体详情 MET目标详情 使用细节 References for anti-MET antibody (ABIN671661) 图像 回页首 |
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| 状态 | Liquid |
| 浓度 | 1 μg/μL |
| 缓冲液 | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
| 储存液 | Sodium azide |
| 注意事项 | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| 储存条件 | -20 °C |
| 储存方法 | Store at -20°C |
| 有效期 | 12 months |
References for anti-MET antibody (ABIN671661)MET抗体详情 MET目标详情 使用细节 贮存及处理 图像 回页首 |
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| 有引用在： |
Wang, Tang, Shen, Chen, Chen, Luo, Ge: "Hepatocyte growth factor (HGF) optimizes oral traumatic ulcer healing of mice by reducing inflammation." in: Cytokine, Vol. 99, pp. 275-280, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Yu, He, Jiang, He, Fan, Wang, Geng, Dong: "Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors." in: Acta histochemica, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human). Further details: Sample: epithelial ovarian tissue Gao, Bing, Li, Yang, Li, Chen: "Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 546, 2013 Method employed by authors: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human). Further details: Sample: colon carcinoma/ |
图像MET抗体详情 MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN671661) 回页首 |
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| 厂商提供的图像 |
Formalin-fixed and paraffin-embedded mouse intestine labeled with Anti-C-Met/Met/HGFR...
Formalin-fixed and paraffin embedded human gastric carcinoma labeled Anti-C-Met Polyc...
Mouse nephrocytes probed with Rabbit Anti-Met (c Met) Polyclonal Antibody .
Formalin-fixed and paraffin embedded human gastric carcinoma labeled Anti-C-Met Polyc...
Paraformaldehyde-fixed, paraffin embedded mouse brain, Antigen retrieval by boiling i...
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