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抗Human KIT 抗体:
the missense mutation p.Arg682His, the g.77784972T>C variant at KIT and the g.20147039C>T variant at MITF (显示 MITF 抗体) are the main influence on the extent of white facial markings
Accumulating mutations in series of haplotypes at the KIT and MITF (显示 MITF 抗体) loci are major determinants of white markings in Franches-Montagnes horses.
FGF7 (显示 FGF7 抗体) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (显示 KITLG 抗体) signaling pathway.
c-kit is primarily expressed in the spermatogonia and spermatocytes of goat testes.
mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.
Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.
Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.
findings that the CD56 (显示 NCAM1 抗体) and CD117 expression levels are lower in advanced stages than earlier stages and that LDH level and CD117 expression have an inverse relationship in patients with newly diagnosed multiple myeloma (MM) suggest that CD56 (显示 NCAM1 抗体) and CD117 expressions may be prognostic markers for MM.
activation of KIT by a gain-of-function, somatic mutation is a novel mechanism of resistance to crizotinib in ROS1 rearranged non-small cell lung cancer
Mutational activation of Kit-, Ras/Raf (显示 RAF1 抗体)/Erk (显示 EPHB2 抗体)- and Akt (显示 AKT1 抗体)- pathways indicate the biological importance of these pathways and their components as potential targets for therapy.
KIT exon 11 codons 557-558 deletion enhanced CXCL12 (显示 CXCL12 抗体)-mediated GIST cell migration.
Data show the kinetic behavior of a G-rich sequence located within the c-KIT proximal promoter (kit2) in the presence of monovalent cations K+ and Na+.
Long-term follow-up of patients with metastatic GIST treated with regorafenib suggests particular benefit among patients with primary KIT exon 11 mutations and those with SDH (显示 SARDH 抗体)-deficient GIST. Dose modifications are frequently required to manage treatment-related toxicities
c-kit-positive cells derived from right atrium tissue were associated with serum BNP (显示 BNC2 抗体)
For hot spots in KIT and PDGFRA (显示 PDGFRA 抗体) genes, 23 out of 146 KIT/PDGFRA (显示 PDGFRA 抗体) wild-type cases carried mutations according to next-generation sequencing (NGS).
KIT and DNMT1 (显示 DNMT1 抗体) co-expression promotes, whereas dual inactivation of them suppresses, lung cancer cell proliferation and metastatic growth in vitro and in vivo, in a synergistic manner.
Data indicate that BRAF (显示 BRAF 抗体), NRAS (显示 NRAS 抗体) and C-KIT melanomas constitute distinct clinico-pathological entities.
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
c-kit receptor tyrosine kinase
, mast/stem cell growth factor receptor
, protein kinase
, tyrosine kinase receptor homolog
, c-kit-related protein
, kit-related kinase 1
, mast/stem cell growth factor receptor-related protein Kit
, proto-oncogene tyrosine-protein kinase Kit-related protein
, tyrosine-protein kinase Kit
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
, Mast/stem cell growth factor receptor
, mast/stem cell growth factor receptor Kit
, transmembrane tyrosine kinase receptor
, proto-oncogene c-Kit
, c-kit receptor
, mast cell growth factor receptor
, proto-oncogene tyrosine-protein kinase Kit
, receptor tyrosine kinase c-kit
, c-KIT gene1
, Proto-oncogene c-Kit
, Tyrosine-protein kinase Kit
, caprine c-kit protein
, p145 c-kit
, piebald trait protein
, soluble KIT variant 1
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein