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ErbB2/Her2 抗体

(Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
ErbB2/Her2 抗体  (AA 23-372) ErbB2/Her2 抗体  (AA 23-372) ErbB2/Her2 抗体 (AA 23-372) (ABIN7444448)

ErbB2/Her2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

ErbB2/Her2 抗体  (AA 22-121) ErbB2/Her2 抗体  (AA 22-121) ErbB2/Her2 抗体 (AA 22-121) (ABIN515370)

ErbB2/Her2 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3B1 unconjugated

ErbB2/Her2 抗体  (C-Term) ErbB2/Her2 抗体  (C-Term) ErbB2/Her2 抗体 (C-Term) (ABIN6254225)

ErbB2/Her2 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Cow, Pig, Hamster, 兔, Cat, 小鸡, 驴, 山羊, 豚鼠, 绵羊, Avian WB 宿主: 山羊 Polyclonal unconjugated

ErbB2/Her2 抗体 by Grade

Find ErbB2/Her2 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by 适用

Find ErbB2/Her2 抗体 for a variety of species such as anti-Human ErbB2/Her2, anti-Mouse ErbB2/Her2, anti-Rat ErbB2/Her2. The species listed below are among those available. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by 应用范围

Find ErbB2/Her2 抗体 validated for a specific application such as WB, ELISA, DB, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by 抗体来源

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ErbB2/Her2 抗体 by 抗原表位

Find ErbB2/Her2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ErbB2/Her2 抗体. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by 克隆

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ErbB2/Her2 抗体 by 标记

Find ErbB2/Her2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

ErbB2/Her2 抗体 by Fragment

Find ErbB2/Her2 抗体 with a specific Fragment. The Fragment listed below are among those available. Click on a link to go to the corresponding products.

Popular ErbB2/Her2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7444448
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), PLA
Validations
  • (7)
Cat. No. ABIN515370
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (7)
Cat. No. ABIN6254225
Quantity 600 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (10)
Cat. No. ABIN6255774
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (12)
Cat. No. ABIN6256630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, IP, ICC
Validations
  • (12)
Cat. No. ABIN6256054
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN6140248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6939319
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6939316
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7139095
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN515369
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS, Coat
Validations
  • (4)
Cat. No. ABIN6939327
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN870539
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN969111
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN3029510
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our ErbB2/Her2 抗体

Helsen, Hammill, Lau, Mwawasi, Afsahi, Bezverbnaya, Newhook, Hayes, Aarts, Bojovic, Denisova, Kwiecien, Brain, Derocher, Milne, Nelson, Bramson: "The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity." in: Nature communications, Vol. 9, Issue 1, pp. 3049, (2019) (PubMed).

Bielamowicz, Fousek, Byrd, Samaha, Mukherjee, Aware, Wu, Orange, Sumazin, Man, Joseph, Hegde, Ahmed: "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma." in: Neuro-oncology, Vol. 20, Issue 4, pp. 506-518, (2019) (PubMed).

Steele, Chakrabarti, Wang, Biesiada, Holokai, Chang, Nowacki, Hawkins, Mahe, Sundaram, Shroyer, Medvedovic, Helmrath, Ahmad, Zavros: "An Organoid-Based Preclinical Model of Human Gastric Cancer." in: Cellular and molecular gastroenterology and hepatology, Vol. 7, Issue 1, pp. 161-184, (2019) (PubMed).

Erlangga, Wolff, Poth, Peltzer, Nahnsen, Spielberg, Timrott, Woller, Kühnel, Manns, Saborowski, Vogel, Saborowski: "Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).

Wang, Guo, Feng, Zhang, Xiao, Di, Chen, Zhang: "Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer." in: Oncology reports, Vol. 39, Issue 5, pp. 2147-2159, (2018) (PubMed).

Li, Ma, Zheng, Zhang: "GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 80, (2018) (PubMed).

Wang, Her, Hu, Chen, Tung, Wu, Hsu, Lee, Jin, Hwang, Chen, Huang, Liao: "ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 15, pp. E3129-E3138, (2018) (PubMed).

Scrima, Zito Marino, Oliveira, Marinaro, La Mantia, Rocco, De Marco, Malanga, De Rosa, Rizzuto, Botti, Franco, Zoppoli, Viglietto: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, (2017) (PubMed).

Qi, Zhou, Lu, Yuan, Li, Wu, Huang, Shen, Zhao, Fu, Chu, Wang, Ren, Ma, Chen: "Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips." in: Biochemical and biophysical research communications, Vol. 484, Issue 2, pp. 248-254, (2017) (PubMed).

Seigel, Sharma, Hackam, Shah: "HER2/ERBB2 immunoreactivity in human retinoblastoma." in: Tumour biology, Vol. 37, Issue 5, pp. 6135-42, (2016) (PubMed).

Aliases for ErbB2/Her2 抗体

erb-b2 receptor tyrosine kinase 2 (ERBB2) 抗体
erb-b2 receptor tyrosine kinase 2 (Erbb2) 抗体
erb-b2 receptor tyrosine kinase 2 (erbb2) 抗体
c-erbB2 抗体
c-neu 抗体
CD340 抗体
erb2 抗体
Erbb-2 抗体
HER-2 抗体
HER-2/neu 抗体
HER2 抗体
mKIAA3023 抗体
MLN 19 抗体
NEU 抗体
Neu 抗体
NGL 抗体
TKR1 抗体
wu:fv70f10 抗体
zgc:63601 抗体
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