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ABI1 抗体

(Abl-Interactor 1 (ABI1))
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10\;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011].
ABI1 抗体  (AA 1-182) ABI1 抗体  (AA 1-182) ABI1 抗体 (AA 1-182) (ABIN7436735)

ABI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

ABI1 抗体  (AA 180-230) ABI1 抗体  (AA 180-230) ABI1 抗体 (AA 180-230) (ABIN7265359)

ABI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

ABI1 抗体  (N-Term) ABI1 抗体  (N-Term) ABI1 抗体 (N-Term) (ABIN3043515)

ABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

ABI1 抗体 by 适用

Find ABI1 抗体 for a variety of species such as anti-Human ABI1, anti-Rat ABI1, anti-Mouse ABI1. The species listed below are among those available. Click on a link to go to the corresponding products.

ABI1 抗体 by 应用范围

Find ABI1 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

ABI1 抗体 by 抗体来源

Find ABI1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

ABI1 抗体 by 抗原表位

Find ABI1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ABI1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ABI1 抗体. Click on a link to go to the corresponding products.

ABI1 抗体 by 克隆

Find ABI1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

ABI1 抗体 by 标记

Find ABI1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ABI1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (11)
Cat. No. ABIN7436735
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN7265359
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN3043515
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7241930
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (3)
  • (2)
Cat. No. ABIN548494
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN3043678
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, FACS
Validations
  • (4)
Cat. No. ABIN652475
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN4952702
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, FACS, EIA
Validations
  • (4)
Cat. No. ABIN453492
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (3)
Cat. No. ABIN5647478
Quantity 0.08 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN3029824
Quantity 100 μg
Datasheet Datasheet
Reactivity Hamster, Human, Mouse
Application WB, IP, IHC (p)
Validations
  • (3)
Cat. No. ABIN1449186
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IF/ICC
Validations
  • (3)
Cat. No. ABIN3003792
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN675953
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6748109
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ABI1 抗体

Chorzalska, Kim, Roder, Tepper, Ahsan, Rao, Olszewski, Yu, Terentyev, Morgan, Treaba, Zhao, Liang, Gruppuso, Dubielecka: "Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia." in: Stem cells and development, Vol. 26, Issue 9, pp. 656-677, (2017) (PubMed).

Trinh-Trang-Tan, Bigot, Picot, Lecomte, Kordeli: "AlphaII-spectrin participates in the surface expression of cell adhesion molecule L1 and neurite outgrowth." in: Experimental cell research, Vol. 322, Issue 2, pp. 365-80, (2014) (PubMed).

McNeill, Klöckner-Bormann, Roesler, Talton, Moechars, Clagett-Dame: "Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development." in: Developmental biology, Vol. 353, Issue 2, pp. 331-43, (2011) (PubMed).

Cui, Yu, Dong, Chen, Zhang, Liu: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." in: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).

Tani, Sato, Sukezane, Kojima, Hirose, Hanafusa, Shishido: "Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21685-92, (2003) (PubMed).

Yamamoto, Suzuki, Sakaki: "Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease." in: Gene, Vol. 271, Issue 2, pp. 159-69, (2001) (PubMed).

Fan, Goff: "Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7591-601, (2000) (PubMed).

Ziemnicka-Kotula, Xu, Gu, Potempska, Kim, Jenkins, Trenkner, Kotula: "Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13681-92, (1998) (PubMed).

Taki, Shibuya, Taniwaki, Hanada, Morishita, Bessho, Yanagisawa, Hayashi: "ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23)." in: Blood, Vol. 92, Issue 4, pp. 1125-30, (1998) (PubMed).

Biesova, Piccoli, Wong: "Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth." in: Oncogene, Vol. 14, Issue 2, pp. 233-41, (1997) (PubMed).

Aliases for ABI1 抗体

abl interactor 1 (ABI1) 抗体
abl-interactor 1 (Abi1) 抗体
abl-interactor 1a (abi1a) 抗体
abl interactor 1 S homeolog (abi1.S) 抗体
abl interactor 1 (abi1) 抗体
abl-interactor 1b (abi1b) 抗体
Abl-interactor 1 (Bm1_44660) 抗体
Abl interactor 1 (abi1) 抗体
abl-interactor 1 (LOAG_04356) 抗体
abl interactor 1 (Abi1) 抗体
ABI-1 抗体
abi-1 抗体
abi1 抗体
ABI1 抗体
ABLBP4 抗体
DKFZp469P1319 抗体
E3B1 抗体
E3b1 抗体
e3b1 抗体
MGC84356 抗体
NAP1 抗体
NAP1BP 抗体
nap1bp 抗体
SSH3BP 抗体
ssh3bp 抗体
SSH3BP1 抗体
Ssh3bp1 抗体
ssh3bp1 抗体
wu:fc66g09 抗体
wu:fe48a10 抗体
wu:fk56a10 抗体
zgc:73174 抗体
zgc:153534 抗体
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