ATP7B 抗体
(ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008].
recommended
recommended
ATP7B 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB19038 unconjugated
recommended
ATP7B 抗体 by 适用
Find ATP7B 抗体 for a variety of species such as anti-Human ATP7B, anti-Mouse ATP7B, anti-Rat ATP7B. The species listed below are among those available. Click on a link to go to the corresponding products.
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ATP7B 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ATP7B 抗体. Click on a link to go to the corresponding products.
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Popular ATP7B 抗体
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Reactivity
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Validations
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Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN2485167
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN2485164
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our ATP7B 抗体
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." in: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).: "The release and detection of copper ions from ultrasmall theranostic Cu2-xSe nanoparticles." in: Nanoscale, Vol. 11, Issue 24, pp. 11819-11829, (2019) (PubMed).
: "Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma." in: Frontiers in oncology, Vol. 9, pp. 958, (2019) (PubMed).
: "The loss of copper is associated with the increase in copper metabolism MURR domain 1 in ischemic hearts of mice." in: Experimental biology and medicine (Maywood, N.J.), Vol. 243, Issue 9, pp. 780-785, (2018) (PubMed).
: "A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals." in: Journal of the American Chemical Society, (2018) (PubMed).
: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." in: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).
: "A Chinese herbal Formula, Chang-Wei-Qin, Synergistically Enhances Antitumor Effect of Oxaliplatin." in: Pathology oncology research : POR, Vol. 21, Issue 2, pp. 389-97, (2015) (PubMed).
: "Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo." in: Biochemical pharmacology, Vol. 95, Issue 1, pp. 28-37, (2015) (PubMed).
: "Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease." in: PLoS ONE, Vol. 8, Issue 7, pp. e66526, (2013) (PubMed).
: "Is ATP7B a predictive marker in patients with ovarian carcinoma treated with platinum-taxane combination chemotherapy?" in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 23, Issue 1, pp. 60-4, (2012) (PubMed).
Aliases for ATP7B 抗体
ATPase copper transporting beta (ATP7B) 抗体ATPase, Cu++ transporting, beta polypeptide (Atp7b) 抗体
ATPase copper transporting beta (Atp7b) 抗体
ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (atp7b) 抗体
copper-transporting ATPase 2 (LOC592143) 抗体
ATPase, Cu++ transporting, beta polypeptide (atp7b) 抗体
ATPase copper transporting beta (atp7b) 抗体
Atp7a 抗体
ATP7B 抗体
Hts 抗体
PINA 抗体
PWD 抗体
tx 抗体
WC1 抗体
WD 抗体
Wd 抗体
WND 抗体
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