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Ataxin 2 蛋白

(Ataxin 2 (ATXN2))

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12, and it has been determined that the diseased allele contains 37-50 CAG repeats, compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined. [provided by RefSeq, Jan 2010].

recommended

Ataxin 2 Protein (ATXN2) (AA 1-1313) (Strep Tag) (ABIN3089810)

Crystallography grade ATXN2 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

Ataxin 2 Protein (ATXN2) (AA 1-165) (His tag) (ABIN7121916)

ATXN2 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

Ataxin 2 Protein (ATXN2) (AA 1214-1313) (GST tag) (ABIN1346193)

ATXN2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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Popular Ataxin 2 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Ataxin 2 Protein (ATXN2) (AA 1-1313) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3089810

Quantity 1 mg

Datasheet Datasheet

Ataxin 2 Protein (ATXN2) (AA 1-165) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7121916

Quantity 50 μg

Datasheet Datasheet

Ataxin 2 Protein (ATXN2) (AA 1214-1313) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346193

Quantity 10 μg

Datasheet Datasheet

Ataxin 2 Protein (ATXN2) (AA 1-1285) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3131964

Quantity 1 mg

Datasheet Datasheet

Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505038

Quantity 100 μg

Datasheet Datasheet

Aliases for Ataxin 2 蛋白

ataxin 2 (ATXN2) 蛋白
ataxin 2 (Atxn2) 蛋白
ataxin 2 L homeolog (atxn2.L) 蛋白
9630045M23Rik 蛋白
ASL13 蛋白
ATX2 蛋白
ATXN2 蛋白
AW544490 蛋白
MGC115230 蛋白
SCA2 蛋白
Sca2 蛋白
TNRC13 蛋白

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