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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN1394161 | IHC (p) WB | Biotin | Rabbit | IgG | Log in to see | Polyclonal | 0 | ||
1 | ABIN1386055 | IF (p) IHC (p) WB | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
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抗原 | Pancreas Specific Transcription Factor, 1a (PTF1A) 抗体 |
适用 | 人, 小鼠, 大鼠 其他选择 |
宿主 | 兔 其他选择 |
克隆类型 | |
标记 | This PTF1A antibody is conjugated to HRP 其他选择 |
应用范围 |
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
其他选择
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Supplier | Log in to see |
PTF1A抗体详情PTF1A目标详情 使用细节 贮存及处理 图像 |
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纯化方法 | Purified by Protein A. |
免疫原 | KLH conjugated synthetic peptide derived from human PTF1A |
亚型 | IgG |
Plasmids, Primers & others | |
PTF1A目标详情PTF1A抗体详情 使用细节 贮存及处理 图像 回页首 |
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抗原 | |
别名 | Ptf1a (PTF1A Antibody 摘要) |
背景 |
PTF1 is a pancreas-specific protein that functions as a component of the trimeric pancreas transcription factor 1 (PTF1) complex. Localizing to the nucleus, PTF1 contains one basic helix-loop-helix (bHLH) domain and is believed to play an important role in mammalian pancreatic development, functioning as a transcription factor that regulates the specification of all three pancreatic cell types. PTF1 interacts with RBP-Jâ...¹ and, together, they cooperate in regulating the expression of PDX-1 (pancreas/duodenum homeobox protein 1), a key regulator of pancreatic islet development and insulin gene transcription in beta-cells. Loss of functional PTF1 can cause pancreatic progenitors to take on the normal fates of duodenal epithelia. Mutations in the gene encoding PTF1 lead to diabetes mellitus and cerebellar hypoplasia/agenesis, suggesting that PTF1 also plays and important role in cerebellar neurogenesis. Subcellular location: Extracellular Synonyms: PTF1-p48, bHLH transcription factor p48, bHLHa29, Class A basic helix-loop-helix protein 29, Class II bHLH protein PTF1A, Exocrine pancreas specic transcription factor p48, p48 DNA binding subunit of transcription factor PTF1, p48 DNA-binding subunit of transcription factor PTF1, Pancreas specic transcription factor 1a, Pancreas transcription factor 1 subunit alpha, Pancreas-specic transcription factor 1a, PTF 1A, PTF1 p48, PTF1-p48, Ptf1a, PTF1A_HUMAN, PTF1P48. |
途径 | Retinoic Acid Receptor Signaling Pathway |
使用细节PTF1A抗体详情 PTF1A目标详情 贮存及处理 图像 回页首 |
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应用备注 |
WB 1:100-1000 IHC-P 1:100-500 |
限制 | 仅限研究用 |
贮存及处理PTF1A抗体详情 PTF1A目标详情 使用细节 图像 回页首 |
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状态 | Liquid |
浓度 | 1 μg/μL |
缓冲液 | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin. |
储存液 | Gentamicin sulfate |
注意事项 | This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
注意事项 | Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. |
储存条件 | 4 °C |
储存方法 | Store at 4°C |
有效期 | 12 months |