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FDPS 抗体

(Farnesyl Diphosphate Synthase (FDPS))
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008].
FDPS 抗体 FDPS 抗体 FDPS 抗体 (ABIN2856081)

FDPS 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated

FDPS 抗体  (AA 1-419) FDPS 抗体  (AA 1-419) FDPS 抗体 (AA 1-419) (ABIN7152571)

FDPS 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

FDPS 抗体  (AA 1-419) FDPS 抗体  (AA 1-419) FDPS 抗体 (AA 1-419) (ABIN7442606)

FDPS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

FDPS 抗体 by 适用

Find FDPS 抗体 for a variety of species such as anti-Human FDPS, anti-Rat FDPS, anti-Mouse FDPS. The species listed below are among those available. Click on a link to go to the corresponding products.

FDPS 抗体 by 应用范围

Find FDPS 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FDPS 抗体 by 抗体来源

Find FDPS 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FDPS 抗体 by 抗原表位

Find FDPS 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FDPS 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FDPS 抗体. Click on a link to go to the corresponding products.

FDPS 抗体 by 克隆

Find FDPS 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

FDPS 抗体 by 标记

Find FDPS 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FDPS 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), ICC, IF
Validations
  • (5)
Cat. No. ABIN2856081
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (4)
Cat. No. ABIN7152571
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7442606
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN6140569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (2)
  • (3)
Cat. No. ABIN1882080
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN515584
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7247144
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (1)
Cat. No. ABIN545249
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (6)
  • (2)
Cat. No. ABIN389054
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6242923
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN515583
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN515586
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7267129
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1867898
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (2)
Cat. No. ABIN952387
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our FDPS 抗体

Sousa, Auriola, Mönkkönen, Määttä: "Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells." in: BMC cancer, Vol. 15, pp. 4, (2015) (PubMed).

Todenhöfer, Hennenlotter, Kühs, Gerber, Gakis, Vogel, Aufderklamm, Merseburger, Knapp, Stenzl, Schwentner: "Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?" in: World journal of urology, Vol. 31, Issue 2, pp. 345-50, (2013) (PubMed).

Zhang, Dai, Wang: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).

Ishimoto, Tachibana, Hanano, Yamasaki, Nakamura, Kawai, Urano, Tanaka, Hamakubo, Sakai, Kodama, Doi: "Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells." in: The Biochemical journal, Vol. 429, Issue 2, pp. 347-57, (2010) (PubMed).

Räikkönen, Mönkkönen, Auriola, Mönkkönen: "Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells." in: Biochemical pharmacology, Vol. 79, Issue 5, pp. 777-83, (2010) (PubMed).

Li, Herold, Kimmel, Müller, Rincon-Orozco, Kunzmann, Herrmann: "Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 8118-24, (2009) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Wilkin, Kutsunai, Edwards et al.: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).

Sheares, White, Molowa, Chan, Ding, Kroon, Bostedor, Karkas: "Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells." in: Biochemistry, Vol. 28, Issue 20, pp. 8129-35, (1990) (PubMed).

Aliases for FDPS 抗体

Farnesyl pyrophosphate synthase (Fpps) 抗体
farnesyl diphosphate synthase (fdps) 抗体
farnesyl diphosphate synthase L homeolog (fdps.L) 抗体
farnesyl pyrophosphate synthase (MGG_08649) 抗体
farnesyl pyrophosphate synthetase (TP03_0857) 抗体
farnesyl pyrophosphate synthetase (Tb09.160.4300) 抗体
farnesyl-pyrophosphate synthetase (fpp) 抗体
farnesyl pyrophosphate synthetase (BBOV_I000120) 抗体
FDP synthase (fps) 抗体
Farnesyl pyrophosphate synthetase (fpps) 抗体
farnesyl diphosphate synthase (FDPS) 抗体
farnesyl diphosphate synthase (Fdps) 抗体
farnesyl diphosphate synthetase (Fdps) 抗体
farnesyl pyrophosphate synthase 1 (fps1) 抗体
(2E 抗体
16.m00760 抗体
6030492I17Rik 抗体
Ac2-125 抗体
AI256750 抗体
CG12389 抗体
DDBDRAFT_0206220 抗体
DDBDRAFT_0215017 抗体
DDB_0206220 抗体
DDB_0215017 抗体
Dmel\\CG12389 抗体
DmFPPS 抗体
DmFPPSase 抗体
DmFPS 抗体
Fdpsl1 抗体
fpps 抗体
FPPS 抗体
FPS 抗体
fps 抗体
l(2)k06103 抗体
mKIAA1293 抗体
NCU01175.1 抗体
v(2)k03514 抗体
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