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high S100B (显示 S100B 抗体) expression in Multiple Sclerosis (MS) patient samples suggests its usefulness as a diagnostic biomarker for MS.
the underlying mechanism of S100B (显示 S100B 抗体)-mediated effects on cancer stem-like cell stemness was not dependent on its binding with a receptor for advanced glycation end products (RAGE (显示 AGER 抗体)), but might be through intracellular regulation, through the inhibition of p53 (显示 TP53 抗体) expression and phosphorylation.
Data show that a high serum S100beta protein level, hypertension, and high low density lipoprotein-cholesterol (LDL-C) level were the independent risk factors for cerebral small vessel disease (SVD (显示 KCNJ13 抗体)).
the serum concentrations of S100B (显示 S100B 抗体) are increased in bipolar disorder patients.
Levels of NSE (显示 ENO2 抗体) and S100B (显示 S100B 抗体) are still elevated 1 year postpartum in women who have had preeclampsia in contrast to women with previous normal pregnancies.
In vitro experiments using repeated freeze-thaw procedures showed an intracellular up-regulation of S100B (显示 S100B 抗体) in normal and vitiligo (显示 MITF 抗体) melanocytes before an extensive release in the environment.
Acute paranoid schizophrenia inpatients present a day/night change of S100B (显示 S100B 抗体) serum levels at admission that disappears at discharge.
Compared to the control, the S100B (显示 S100B 抗体)/GAPDH (显示 GAPDH 抗体) mRNA ratio was significantly decreased in chronic liver diseases (p = 0.006) and most decreased in chronic hepatitis C patients (p = 0.023). We here evaluated S100B (显示 S100B 抗体) expression as a marker of hepatic nerves in patients with various chronic liver diseases, topographically and semi-quantitatively.
results indicate there were decreased S100B (显示 S100B 抗体) serum levels in bipolar patients in a manic phase after treatment.
Studies indicate that S100 calcium binding protein B protein (S100B (显示 S100B 抗体)) has high affinity for zinc (Zn2+).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21\; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
S-100 calcium-binding protein, beta chain
, S-100 protein subunit beta
, S100 calcium-binding protein, beta (neural)
, protein S100-B