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SHANK3 抗体

(SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012].
SHANK3 抗体  (AA 840-857) (HRP) SHANK3 抗体  (AA 840-857) (HRP) SHANK3 抗体 (AA 840-857) (HRP) (ABIN2485414)

SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 HRP

SHANK3 抗体  (AA 840-857) (FITC) SHANK3 抗体  (AA 840-857) (FITC) SHANK3 抗体 (AA 840-857) (FITC) (ABIN2485413)

SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 FITC

SHANK3 抗体  (AA 840-857) (Alkaline Phosphatase (AP)) SHANK3 抗体  (AA 840-857) (Alkaline Phosphatase (AP)) SHANK3 抗体 (AA 840-857) (Alkaline Phosphatase (AP)) (ABIN2485410)

SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 Alkaline Phosphatase (AP)

SHANK3 抗体 by 适用

Find SHANK3 抗体 for a variety of species such as anti-Rat SHANK3, anti-Mouse SHANK3, anti-Human SHANK3. The species listed below are among those available. Click on a link to go to the corresponding products.

SHANK3 抗体 by 应用范围

Find SHANK3 抗体 validated for a specific application such as WB, IHC, IF, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SHANK3 抗体 by 抗体来源

Find SHANK3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SHANK3 抗体 by 抗原表位

Find SHANK3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SHANK3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SHANK3 抗体. Click on a link to go to the corresponding products.

SHANK3 抗体 by 克隆

Find SHANK3 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SHANK3 抗体 by 标记

Find SHANK3 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SHANK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485414
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485413
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485410
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485412
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485417
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485416
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485411
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485403
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485405
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485402
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (4)
Cat. No. ABIN863129
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741251
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741264
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741263
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN1741260
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SHANK3 抗体

Tao-Cheng, Toy, Winters, Reese, Dosemeci: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).

Wei, Ma, Ding, Jin, Liu, Chang, Hu, Yu: "Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder." in: Neurochemical research, Vol. 41, Issue 11, pp. 3129-3137, (2016) (PubMed).

Wei, Ma, Liu, Ding, Jin, Wang, Hu, Yu: "Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism." in: Biochimica et biophysica acta, Vol. 1862, Issue 10, pp. 1918-25, (2016) (PubMed).

Benthani, Tran, Currey, Ng, Giry-Laterriere, Carey, Kohonen-Corish, Pangon: "Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform." in: International journal of molecular sciences, Vol. 16, Issue 5, pp. 11522-30, (2015) (PubMed).

Braude, Vijayakumar, Baumgarner, Laurine, Jones, Jones, Pyott: "Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear." in: Hearing research, Vol. 321, pp. 52-64, (2015) (PubMed).

Farley, Swulius, Waxham: "Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities." in: Neuroscience, Vol. 304, pp. 286-301, (2015) (PubMed).

Mayanagi, Yasuda, Sobue: "PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 42, pp. 14327-40, (2015) (PubMed).

Hagmeyer, Mangus, Boeckers, Grabrucker: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).

Duffney, Wei, Cheng, Liu, Smith, Kittler, Yan: "Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 40, pp. 15767-78, (2013) (PubMed).

Durand, Perroy, Loll, Perrais, Fagni, Bourgeron, Montcouquiol, Sans: "SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism." in: Molecular psychiatry, Vol. 17, Issue 1, pp. 71-84, (2012) (PubMed).

Aliases for SHANK3 抗体

SH3 and multiple ankyrin repeat domains 3 (SHANK3) 抗体
SH3 and multiple ankyrin repeat domains protein 3 (shank3) 抗体
SH3 and multiple ankyrin repeat domains 3 (Shank3) 抗体
AI841104 抗体
DEL22q13.3 抗体
PROSAP2 抗体
Prosap2 抗体
PSAP2 抗体
SCZD15 抗体
Shank3b 抗体
SPANK-2 抗体
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