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MED12 抗体

(Mediator Complex Subunit 12 (MED12))
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009].
MED12 抗体  (C-Term) MED12 抗体  (C-Term) MED12 抗体 (C-Term) (ABIN6242936)

MED12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52354 unconjugated

MED12 抗体  (AA 1742-2011) MED12 抗体  (AA 1742-2011) MED12 抗体 (AA 1742-2011) (ABIN7159104)

MED12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

MED12 抗体  (AA 1829-1941) MED12 抗体  (AA 1829-1941) MED12 抗体 (AA 1829-1941) (ABIN564287)

MED12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated

MED12 抗体 by Grade

Find MED12 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MED12 抗体 by 适用

Find MED12 抗体 for a variety of species such as anti-Mouse MED12, anti-Human MED12, anti-Rat MED12. The species listed below are among those available. Click on a link to go to the corresponding products.

MED12 抗体 by 应用范围

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MED12 抗体 by 抗体来源

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MED12 抗体 by 抗原表位

Find MED12 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MED12 抗体 by 克隆形成能力

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MED12 抗体 by 克隆

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MED12 抗体 by 标记

Find MED12 抗体 with a specific conjugate such as FITC, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MED12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN6242936
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7159104
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
  • (1)
Cat. No. ABIN564287
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7243679
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN5583384
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN5675220
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, WB, IHC (p), IHC (fro)
Validations
Cat. No. ABIN5675221
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6976774
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6977635
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6978496
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6979294
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6980150
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6982032
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6981060
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6983572
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MED12 抗体

Cao, Jiang, Wang, Zhang, Al-Hendy, Mamillapalli, Kallen, Kodaman, Taylor, Li, Huang: "H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas." in: Oncogene, Vol. 38, Issue 27, pp. 5356-5366, (2019) (PubMed).

Shen, Szewczyk, Eram, Smil, Kaniskan, de Freitas, Senisterra, Li, Schapira, Brown, Arrowsmith, Barsyte-Lovejoy, Liu, Vedadi, Jin: "Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6." in: Journal of medicinal chemistry, Vol. 59, Issue 19, pp. 9124-9139, (2016) (PubMed).

Vogl, Reiprich, Küspert, Kosian, Schrewe, Nave, Wegner: "Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 15, pp. 6679-90, (2013) (PubMed).

Wagner, DeLuca: "Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription." in: PLoS ONE, Vol. 8, Issue 10, pp. e78242, (2013) (PubMed).

Rienzo, Casamassimi, Schiano, Grimaldi, Infante, Napoli: "Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation." in: Biochimie, Vol. 94, Issue 8, pp. 1828-32, (2012) (PubMed).

Miyanari, Torres-Padilla: "Control of ground-state pluripotency by allelic regulation of Nanog." in: Nature, Vol. 483, Issue 7390, pp. 470-3, (2012) (PubMed).

Pérot, Croce, Ribeiro, Lagarde, Velasco, Neuville, Coindre, Stoeckle, Floquet, MacGrogan, Chibon: "MED12 alterations in both human benign and malignant uterine soft tissue tumors." in: PLoS ONE, Vol. 7, Issue 6, pp. e40015, (2012) (PubMed).

Valdez, Nieto, Murray, Li, Wang, Champlin, Andersson: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." in: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).

Langlais, Couture, Sylvain-Drolet, Drouin: "A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 2, pp. 348-59, (2011) (PubMed).

DAlessio, Ng, Willenbring, Tjian: "Core promoter recognition complex changes accompany liver development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 10, pp. 3906-11, (2011) (PubMed).

Aliases for MED12 抗体

mediator complex subunit 12 (MED12) 抗体
mediator complex subunit 12 (Med12) 抗体
mediator complex subunit 12 (med12) 抗体
230kDa 抗体
ARC240 抗体
CAGH45 抗体
FGS1 抗体
HOPA 抗体
MED12S 抗体
Mopa 抗体
OHDOX 抗体
OKS 抗体
OPA-1 抗体
OPA1 抗体
TNRC11 抗体
Tnrc11 抗体
TRAP230 抗体
Trap230 抗体
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