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抗Human CADM1 抗体:
抗Mouse (Murine) CADM1 抗体:
抗Rat (Rattus) CADM1 抗体:
Human Polyclonal CADM1 Primary Antibody for ICC, IF - ABIN152528
Biederer, Sara, Mozhayeva, Atasoy, Liu, Kavalali, Südhof: SynCAM, a synaptic adhesion molecule that drives synapse assembly. in Science (New York, N.Y.) 2002
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Human Polyclonal CADM1 Primary Antibody for IF (p), IHC (p) - ABIN738351
Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011
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Human Polyclonal CADM1 Primary Antibody for IHC, ELISA - ABIN1585332
Ballester, Gonin, Rodenas, Bernaudin, Rouzier, Coutant, Daraï: Eutopic endometrium and peritoneal, ovarian and colorectal endometriotic tissues express a different profile of nectin-1, -3, -4 and nectin-like molecule 2. in Human reproduction (Oxford, England) 2012
Mammalian Monoclonal CADM1 Primary Antibody for ISt, IHC - ABIN1304990
Rollenhagen, Kuckuck, Ulm, Hartmann, Galuska, Geyer, Geyer, Mühlenhoff: Polysialylation of the synaptic cell adhesion molecule 1 (SynCAM 1) depends exclusively on the polysialyltransferase ST8SiaII in vivo. in The Journal of biological chemistry 2012
These findings suggest that CADM1 expression is a novel prognostic factor for peripheral T cell lymphoma, not otherwise specified
miR (显示 MLXIP 抗体)-21 enhances chemo-resistance in tongue cancer cells via directly targeting CADM1, and an inverse correlation between miR (显示 MLXIP 抗体)-21 and CADM1 expression in vivo. MiR (显示 MLXIP 抗体)-21 overexpression is attributed to MYCN (显示 MYCN 抗体)-mediated transcriptional regulation, which is also predictive for a worse prognosis in tongue cancer
We conclude that CADM1 was not associated with cell-cell interaction between lymphoma cells and macrophages, although CADM1 may be a useful marker of ATLL for diagnostic procedures.
miR (显示 MLXIP 抗体)-21 overexpression promotes cardiac fibrosis via STAT3 (显示 STAT3 抗体) signaling pathway by decrease CADM1 expression, indicating miR (显示 MLXIP 抗体)-21 as an important signaling molecule for cardiac fibrotic remodeling and atrial fibrillation.
Pathway analysis of the genes associated with the 46 CpG sites revealed an enrichment of immune system process genes, including LYST (显示 LYST 抗体) (cg16962115, FDR = 1.24E-04), CADM1 (cg21933078, FDR = 1.22E-02) and NFATC1 (显示 NFATC1 抗体) (cg06784563, FDR = 1.46E-02)
CADM1 mRNA expression was highly upregulated in normal tissues compared to esophageal squamous cell carcinoma tissues, indicating that the loss of CADM1 expression influenced the pathogenesis, invasion, and metastasis of ESCC.
Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix (显示 SP7 抗体) respectively. The other markers showed no statistical significance(CD151 (显示 CD151 抗体),ALP (显示 ALP 抗体)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues
Our results suggest that, as in the CNS, CADM1 interactions drive exocytic site assembly and promote actin network formation. These results support the broader hypothesis that the effects of cell-cell contact on beta-cell maturation and function are mediated by the same extracellular protein interactions that drive the formation of the presynaptic exocytic machinery. These interactions may be therapeutic targets for re...
High expression of CADM1 on most HTLV-1-infected cells in the face of enhanced cytotoxic T lymphocyte counterselection implies that CADM1 confers a strong benefit on the virus.
Decreased expression of TSLC1 is associated with the differentiation in ovarian epithelial cancer. TSLC1 might be used as a molecular marker of severity in early stage ovarian cancer, and to help differentiating benign and malignant ovarian tumors.
NF-kB mediated upregulation of CADM1 was identified as a mechanism of TNFalpha (显示 TNF 抗体) induced migration.
The results of this study demonstrate that the synapse-organizing adhesion molecule (显示 NCAM1 抗体) SynCAM 1 has pronounced effects on neuronal connectivity in the hippocampal CA3 (显示 CA3 抗体) area.
Cadm1 is a direct target of NFATc1 (显示 NFATC1 抗体), which is induced by RANKL (显示 TNFSF11 抗体) through epigenetic modification, and regulates osteoclastic bone resorption in a negative feedback manner.
Data show that cell adhesion molecule 1 (SynCAM 1) generally prolongs the lifetime of spines.
This experiments show that the survival rate of adult-generated neurons is increased by overexpressing SynCAM 1
Our study reveals a novel mechanism of chronic NF-kappaB (显示 NFKB1 抗体) activation by CADM1 in HTLV-1 infected cells
Study demonstrates that polysialic acid-SynCAM 1 defines a subpopulation of NG2 (显示 Vcan 抗体) cells and identifies the presence of polysialic acid-NRP2 (显示 NRP2 抗体) in microglia
CADM1 appeared to sustain gap junctional intercellular communication among alpha-cells via homophilic binding and, based on this action, CADM1 appears to prevent excessive secretion of glucagon (显示 GCG 抗体) from alpha-cells.
This study demonistrated that SynCAM 1 in the synaptic organization of the rod visual pathway and provide evidence for novel roles of synaptic adhesion in the structural and functional integrity of ribbon synapses.
Necl-2 co-localizes with ErbB4 (显示 ERBB4 抗体) in hippocampus and and regulates ErbB4 (显示 ERBB4 抗体) signaling in cultured neurons.
Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
, TSLC1/Nectin-like 2/IGSF4
, immunoglobulin superfamily member 4
, immunoglobulin superfamily, member 4
, immunoglobulin superfamily, member 4D variant 1
, immunoglobulin superfamily, member 4D variant 2
, nectin-like 2
, nectin-like protein 2
, spermatogenic immunoglobulin superfamily
, synaptic cell adhesion molecule
, truncated CADM1 protein
, tumor suppressor in lung cancer 1
, cell adhesion molecule 1
, cell adhesion molecule 1 transcript variant 8abc
, immunoglobulin superfamily member 4A
, immunosuperfamily protein Bl2
, immunoglobulin superfamily, member 4A
, secretory isoform of TSLC1
, tumor suppressor in lung cell-1