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CACNA1A 蛋白

(Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010].

recommended

CACNA1A Protein (AA 361-487) (His tag) (ABIN3090203)

Crystallography grade CACNA1A 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

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recommended

CACNA1A Protein (AA 363-489) (His tag) (ABIN3121194)

Crystallography grade CACNA1A 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

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recommended

CACNA1A Protein (AA 1808-2505) (His tag) (ABIN3090205)

Crystallography grade CACNA1A 宿主: 人宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

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CACNA1A 蛋白 by Grade

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CACNA1A 蛋白 by Origin

Find CACNA1A 蛋白 for a variety of species such as anti-Human CACNA1A, anti-Mouse CACNA1A. The species listed below are among those available. Click on a link to go to the corresponding products.

CACNA1A 蛋白 by Source

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CACNA1A 蛋白 by 蛋白类型

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CACNA1A 蛋白 by 应用范围

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Popular CACNA1A 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CACNA1A Protein (AA 361-487) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3090203

Quantity 1 mg

Datasheet Datasheet

CACNA1A Protein (AA 363-489) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3121194

Quantity 1 mg

Datasheet Datasheet

CACNA1A Protein (AA 1808-2505) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3090205

Quantity 1 mg

Datasheet Datasheet

CACNA1A Protein (AA 715-1242) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3090204

Quantity 1 mg

Datasheet Datasheet

CACNA1A Protein (AA 1764-2368) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3134704

Quantity 1 mg

Datasheet Datasheet

CACNA1A Protein (AA 717-1190) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3134705

Quantity 1 mg

Datasheet Datasheet

Aliases for CACNA1A 蛋白

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog (cacna1a.S) 蛋白
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa) 蛋白
calcium voltage-gated channel subunit alpha1 A (CACNA1A) 蛋白
calcium voltage-gated channel subunit alpha1 A (Cacna1a) 蛋白
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a) 蛋白
P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892) 蛋白
alpha1A 蛋白
APCA 蛋白
BccA1 蛋白
BI 蛋白
ca(v)2.1 蛋白
Caca1a 蛋白
CACH4 蛋白
CACN3 蛋白
cacna-a 蛋白
cacna1a 蛋白
CACNL1A4 蛋白
Cacnl1a4 蛋白
cav2.1 蛋白
Cav2.1 蛋白
CAV2.1 蛋白
Ccha1a 蛋白
EA2 蛋白
FHM 蛋白
HPCA 蛋白
la 蛋白
leaner 蛋白
MHP 蛋白
MHP1 蛋白
nmf352 蛋白
rbA-1 蛋白
rkr 蛋白
rocker 蛋白
SCA6 蛋白
si:ch211-237k17.1 蛋白
tg 蛋白
tottering 蛋白

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Popular CACNA1A 蛋白

Aliases for CACNA1A 蛋白

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