电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

DISC1 抗体

(Disrupted in Schizophrenia 1 (DISC1))
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1\;11)(q42.1\;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
DISC1 抗体  (AA 102-261) DISC1 抗体  (AA 102-261) DISC1 抗体 (AA 102-261) (ABIN7439720)

DISC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

DISC1 抗体 DISC1 抗体 DISC1 抗体 (ABIN7266799)

DISC1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

DISC1 抗体 DISC1 抗体 DISC1 抗体 (ABIN7260711)

DISC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

DISC1 抗体 by Grade

Find DISC1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

DISC1 抗体 by 适用

Find DISC1 抗体 for a variety of species such as anti-Human DISC1, anti-Mouse DISC1, anti-Rat DISC1. The species listed below are among those available. Click on a link to go to the corresponding products.

DISC1 抗体 by 应用范围

Find DISC1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

DISC1 抗体 by 抗体来源

Find DISC1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

DISC1 抗体 by 抗原表位

Find DISC1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

DISC1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal DISC1 抗体. Click on a link to go to the corresponding products.

DISC1 抗体 by 克隆

Find DISC1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

DISC1 抗体 by 标记

Find DISC1 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular DISC1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7439720
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN7266799
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7260711
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7150092
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN2473343
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN351527
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
  • (1)
Cat. No. ABIN540418
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
  • (1)
Cat. No. ABIN540381
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5518699
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5013464
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS, EIA
Validations
  • (3)
Cat. No. ABIN951917
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN668541
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN668511
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856299
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN467488
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our DISC1 抗体

El-Hassar, Simen, Duque, Patel, Kaczmarek, Arnsten, Yeckel: "Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels." in: Biological psychiatry, Vol. 76, Issue 6, pp. 476-85, (2014) (PubMed).

Burdick, Kamiya, Hodgkinson, Lencz, DeRosse, Ishizuka, Elashvili, Arai, Goldman, Sawa, Malhotra: "Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding." in: Human molecular genetics, Vol. 17, Issue 16, pp. 2462-73, (2008) (PubMed).

Taya, Shinoda, Tsuboi, Asaki, Nagai, Hikita, Kuroda, Kuroda, Shimizu, Hirotsune, Iwamatsu, Kaibuchi: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).

Duan, Chang, Ge, Faulkner, Kim, Kitabatake, Liu, Yang, Jordan, Ma, Liu, Ganesan, Cheng, Ming, Lu, Song: "Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain." in: Cell, Vol. 130, Issue 6, pp. 1146-58, (2007) (PubMed).

Hayashi, Portaro, Bastos, Guerreiro, Oliveira, Gorrão, Tambourgi, SantAnna, Whiting, Camargo, Konno, Brandon, Camargo: "Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 10, pp. 3828-33, (2005) (PubMed).

Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, (2005) (PubMed).

Brandon, Handford, Schurov, Rain, Pelling, Duran-Jimeniz, Camargo, Oliver, Beher, Shearman, Whiting: "Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders." in: Molecular and cellular neurosciences, Vol. 25, Issue 1, pp. 42-55, (2004) (PubMed).

Hodgkinson, Goldman, Jaeger, Persaud, Kane, Lipsky, Malhotra: "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder." in: American journal of human genetics, Vol. 75, Issue 5, pp. 862-72, (2004) (PubMed).

Taylor, Devon, Millar, Porteous: "Evolutionary constraints on the Disrupted in Schizophrenia locus." in: Genomics, Vol. 81, Issue 1, pp. 67-77, (2003) (PubMed).

Morris, Kandpal, Ma, Austin: "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation." in: Human molecular genetics, Vol. 12, Issue 13, pp. 1591-608, (2003) (PubMed).

Aliases for DISC1 抗体

disrupted in schizophrenia 1 (disc1) 抗体
disrupted in schizophrenia 1 (DISC1) 抗体
disrupted in schizophrenia 1 protein (LOC100580606) 抗体
disrupted in schizophrenia 1 (Disc1) 抗体
C1orf136 抗体
DISC1 抗体
SCZD9 抗体
You are here:
客服