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BCL11A 抗体

(B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
BCL11A 抗体  (AA 1-88) BCL11A 抗体  (AA 1-88) BCL11A 抗体 (AA 1-88) (ABIN526947)

BCL11A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D9 unconjugated

BCL11A 抗体  (N-Term) BCL11A 抗体  (N-Term) BCL11A 抗体 (N-Term) (ABIN6741578)

BCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 小鸡, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

BCL11A 抗体  (AA 1-230) BCL11A 抗体  (AA 1-230) BCL11A 抗体 (AA 1-230) (ABIN7145171)

BCL11A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

BCL11A 抗体 by 适用

Find BCL11A 抗体 for a variety of species such as anti-Human BCL11A, anti-Mouse BCL11A, anti-Rat BCL11A. The species listed below are among those available. Click on a link to go to the corresponding products.

BCL11A 抗体 by 应用范围

Find BCL11A 抗体 validated for a specific application such as WB, ELISA, IP, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find BCL11A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BCL11A 抗体 by 抗原表位

Find BCL11A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BCL11A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BCL11A 抗体. Click on a link to go to the corresponding products.

BCL11A 抗体 by 克隆

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BCL11A 抗体 by 标记

Find BCL11A 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BCL11A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN526947
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (4)
Cat. No. ABIN6741578
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7145171
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN526945
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN790476
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN2781048
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7441184
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN565690
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1989540
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IF
Validations
  • (1)
Cat. No. ABIN6971429
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6746172
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7306288
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN782364
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3028488
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1387845
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our BCL11A 抗体

Martyn, Wienert, Kurita, Nakamura, Quinlan, Crossley: "A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site." in: Blood, Vol. 133, Issue 8, pp. 852-856, (2019) (PubMed).

Martyn, Wienert, Yang, Shah, Norton, Burdach, Kurita, Nakamura, Pearson, Funnell, Quinlan, Crossley: "Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding." in: Nature genetics, Vol. 50, Issue 4, pp. 498-503, (2018) (PubMed).

Wu, Satpathy, Kc, Liu, Murphy, Murphy: "Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo." in: PLoS ONE, Vol. 8, Issue 5, pp. e64800, (2013) (PubMed).

Xu, Sankaran, Ni, Menne, Puram, Kim, Orkin: "Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6." in: Genes & development, Vol. 24, Issue 8, pp. 783-98, (2010) (PubMed).

Chen, Luo, Steinberg, Chui: "BCL11A represses HBG transcription in K562 cells." in: Blood cells, molecules & diseases, Vol. 42, Issue 2, pp. 144-9, (2009) (PubMed).

Uda, Galanello, Sanna, Lettre, Sankaran, Chen, Usala, Busonero, Maschio, Albai, Piras, Sestu, Lai, Dei, Mulas, Crisponi, Naitza, Asunis, Deiana, Nagaraja, Perseu, Satta, Cipollina, Sollaino, Moi, Hirschhorn, Orkin, Abecasis, Schlessinger, Cao: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).

Marafioti, Paterson, Ballabio, Reichard, Tedoldi, Hollowood, Dictor, Hansmann, Pileri, Dyer, Sozzani, Dikic, Shaw, Petrella, Stein, Isaacson, Facchetti, Mason: "Novel markers of normal and neoplastic human plasmacytoid dendritic cells." in: Blood, Vol. 111, Issue 7, pp. 3778-92, (2008) (PubMed).

Liu, Ippolito, Wall, Niu, Probst, Lee, Pulford, Banham, Stockwin, Shaffer, Staudt, Das, Dyer, Tucker: "Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells." in: Molecular cancer, Vol. 5, pp. 18, (2006) (PubMed).

Pulford, Banham, Lyne, Jones, Ippolito, Liu, Tucker, Roncador, Lucas, Ashe, Stockwin, Walewska, Karran, Gascoyne, Mason, Dyer: "The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells." in: Leukemia, Vol. 20, Issue 8, pp. 1439-41, (2006) (PubMed).

Zhu, Hu, Ho, Wang, Yu, Patel, Pi, Choi, Xu, Ganapathy, Kutlar, Kutlar, Tuan et al.: "Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of ..." in: Haematologica, Vol. 102, Issue 12, pp. 1995-2004 (PubMed).

Aliases for BCL11A 抗体

B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) 抗体
B-cell CLL/lymphoma 11A (BCL11A) 抗体
B-cell CLL/lymphoma 11A L homeolog (bcl11a.L) 抗体
B-cell CLL/lymphoma 11A (Bcl11a) 抗体
B-cell CLL/lymphoma 11Aa (bcl11aa) 抗体
2810047E18Rik 抗体
BCL-11A 抗体
bcl11a 抗体
BCL11A-L 抗体
BCL11a-M 抗体
BCL11A-S 抗体
BCL11A-XL 抗体
Ctip1 抗体
CTIP1 抗体
D930021L15Rik 抗体
Evi9 抗体
EVI9 抗体
Evi9a 抗体
Evi9b 抗体
Evi9c 抗体
HBFQTL5 抗体
mKIAA1809 抗体
wu:fi09f10 抗体
zgc:136898 抗体
ZNF856 抗体
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