anti-小鼠 Kin of IRRE Like (Drosophila) 抗体 for Immunofluorescence (Paraffin-embedded Sections)

Recommended Kin of IRRE Like (Drosophila) Antibody (supplied by: Log in to see )

抗原
Kin of IRRE Like (Drosophila) (NEPH1) 抗体
  • NEPH1
  • 6720469N11Rik
  • Kirrel1
  • Neph1
  • nephrin related
  • kirre like nephrin family adhesion molecule 1
  • kin of IRRE like (Drosophila)
  • Smp_104390
  • Smp_140170
  • KIRREL1
  • Kirrel
  • Kirrel1
适用
人, 小鼠, 大鼠
39
31
31
2
2
2
2
2
1
1
1
1
宿主

54
克隆类型
多克隆
标记
Cy3
7
7
3
2
2
2
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
42
30
12
11
11
10
10
10
5
选项
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产品编号 ABIN903751
$ 379.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN903753 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903746 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903756 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903757 IF (p) FITC Rabbit IgG Log in to see Polyclonal 0
1 ABIN903762 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903752 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903754 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal 0
1 ABIN903755 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal 0
1 ABIN873077 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2803578 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal 0

General

抗原 Kin of IRRE Like (Drosophila) (NEPH1) 抗体
适用 人, 小鼠, 大鼠
(39), (31), (31), (2), (2), (2), (2), (2), (1), (1), (1), (1)
宿主
(54)
克隆类型
多克隆
标记 Cy3
(7), (7), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(42), (30), (12), (11), (11), (10), (10), (10), (5)
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产品细节

目标详细情况 使用细节 贮存及处理 图像
纯化方法 Purified by Protein A.
免疫原 KLH conjugated synthetic peptide derived from human KIRREL1/NEPH1
亚型 IgG

目标详细情况

产品细节 使用细节 贮存及处理 图像 回页首
抗原
别名 Kirrel1 (NEPH1 Antibody 摘要)
背景

Neph1(Kirrel) belongs to a family of three closely related transmembrane proteins of the Ig superfamily with a structure similar to that of nephrin. Neph1 consists of a signal peptide, five Ig-like C2-type domains with the middle domain overlapping with a PKD-like domain, an RGD sequence, a transmembrane domain and a cytoplasmic tail. Neph1 is abundantly expressed in the kidney, specifically expressed in podocytes of kidney glomeruli, and plays a significant role in the normal development and function of the glomerular permeability. Neph1 interacts with nephrin in vitro and in vivo, and able to stimulate transcriptional activation in a model system, such as the activation the transcription factor AP-1 via the stimulation of a MAPK module. Neph1 is crucial for the integrity of the slit diaphragm, as Neph1 gene knockout mice results in effacement of glomerular podocytes, heavy proteinuria, and early postnatal death..Tissue specificity:Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.

Subcellular location: Extracellular


Synonyms: Kin of IRRE like Drosophila,Kin of IRRE like,Kin of IRRE like protein 1,Kin of IRRE-like protein 1,Kin of irregular chiasm like protein 1,Kin of irregular chiasm-like protein 1,KIRR1_HUMAN,Kirrel,MGC129542,MGC129543,NEPH 1,NEPH1,Nephrin like protein 1,Nephrin related,Nephrin-like protein 1,KIRR1_HUMAN.
基因ID 55243
途径 Regulation of Actin Filament Polymerization

使用细节

产品细节 目标详细情况 贮存及处理 图像 回页首
应用备注 IF(IHC-P)(1:50-200)
说明

Exitation/Emission: 512,550nm/570,615nm

限制 仅限研究用

贮存及处理

产品细节 目标详细情况 使用细节 图像 回页首
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at 4°C
有效期 12 months