Use your antibodies-online credentials, if available.
抗Mouse (Murine) 抗体:
抗Rat (Rattus) 抗体:
Study showed that a subset of epithelial ovarian cancer (EOC) patients have RacGAP1 (显示 RACGAP1 抗体) overexpression which is associated with advanced tumor stages and poor clinical outcomes. Also, RacGAP1 (显示 RACGAP1 抗体) can positively regulate the activation of RhoA (显示 RHOA 抗体) and Erk (显示 EPHB2 抗体) proteins, thus up-enhance the migration and invasion process of EOC.
Data show that comparing with Ki-67 (显示 MKI67 抗体) and TOP2A (显示 TOP2A 抗体), RacGAP1 (显示 RACGAP1 抗体) allowed for a clearer prognostic statement.
RACGAP1 (显示 RACGAP1 抗体) promotes the metastatic phenotype in uterine carcinosarcoma via a STAT3 (显示 STAT3 抗体)/survivin (显示 BIRC5 抗体) signaling pathway.
High RACGAP1 (显示 RACGAP1 抗体) expression is associated with Basal-like Breast Cancers.
Data suggest that MGCRABGAP (显示 TBC1D21 抗体) is involved in mammalian spermiogenesis by modulating RAB10 (显示 RAB10 抗体).
This study showed that the overexpressions of Ki67 (显示 MKI67 抗体), RacGAP1 (显示 RACGAP1 抗体), and TOP2a (显示 TOP2A 抗体) affect the prognosis of female breast cancer patients adversely
Data confirmed a strong correlation of AURKA (显示 AURKA 抗体) and Wnt (显示 WNT2 抗体)-modulator RACGAP1 (显示 RACGAP1 抗体) gene expression both in the gastric tumor, the tumor-adjacent and the tumor-distant mucosa.
RacGAP1 (显示 RACGAP1 抗体) Is a Novel Downstream Effector of E2F7 (显示 E2F7 抗体)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma
RACGAP1 (显示 RACGAP1 抗体) expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.
central spindle assembly and 2 Plk1 (显示 PLK1 抗体)-dependent phosphorylations are required to establish efficient binding of the Ect2 (显示 ECT2 抗体) BRCT in early cytokinesis.
results indicate that, mTOR (显示 FRAP1 抗体), Bad, or Survivin (显示 BIRC5 抗体) are not required for p120 RasGAP fragment N to protect cells from cell death; conclude that downstream targets of Akt (显示 AKT1 抗体) other than mTORC1, Bad, or survivin (显示 BIRC5 抗体) mediate fragment N-induced protection or that several Akt (显示 AKT1 抗体) effectors can compensate for each other to induce the pro-survival fragment N-dependent responses
RASA1 (显示 RASA1 抗体) catalytic activity is essential for the function and development of lymphatic vessel valves.
These results indicate that the caspase-3 (显示 CASP3 抗体)/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.
Double-deficient RASA1 (显示 RASA1 抗体)-neurofibromin 1 (显示 NF1 抗体) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (显示 NOTCH1 抗体) gene.
Rasa1 (显示 RASA1 抗体) may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model
Regulation of Rasa1 (显示 RASA1 抗体) translation by miR (显示 MLXIP 抗体)-132 was seen in severed axons, demonstrating local function within the axon.
RASA1 (显示 RASA1 抗体) mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS (显示 RASA1 抗体) subject and in the animal model.
MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 (显示 D4S234E 抗体) GTPase activating protein (显示 RASA1 抗体) 1 (RASA1 (显示 RASA1 抗体))
14-3-3 (显示 YWHAQ 抗体) negatively regulates the RGC downstream of the PI3-kinase (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) signaling pathway
Caspase-3 (显示 CASP3 抗体) is a stress intensity sensor that controls cell fate by either initiating a RasGAP (显示 RASA1 抗体) cleavage-dependent cell resistance program or a cell suicide response mediated by akt (显示 AKT1 抗体).
The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.
GTPase activating protein
, male germ cell RacGap
, protein CYK4 homolg
, protein CYK4 homolog
, rac GTPase-activating protein 1
, GTPase-activating protein
, RAS p21 protein activator 1
, ras GTPase-activating protein 1